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Chemical Structure| 478700-27-5 Chemical Structure| 478700-27-5

Structure of Boc-3,3-DiMe-4-oxo-Pro-OH
CAS No.: 478700-27-5

Chemical Structure| 478700-27-5

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Product Details of [ 478700-27-5 ]

CAS No. :478700-27-5
Formula : C12H19NO5
M.W : 257.28
SMILES Code : O=C([C@H](C1(C)C)N(C(OC(C)(C)C)=O)CC1=O)O
MDL No. :MFCD29087486
InChI Key :FRSSMZRTGRGDJR-MRVPVSSYSA-N
Pubchem ID :58682320

Safety of [ 478700-27-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H319
Precautionary Statements:P264-P270-P280-P301+P312+P330-P305+P351+P338-P337+P313-P501

Application In Synthesis of [ 478700-27-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 478700-27-5 ]

[ 478700-27-5 ] Synthesis Path-Downstream   1~2

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  • [ 848444-88-2 ]
  • [ 854375-56-7 ]
  • [ 478700-27-5 ]
YieldReaction ConditionsOperation in experiment
Bacilius lentus protease; In acetonitrile; for 16h;Enzymatic reaction; Example 6: Preparation of (2S)-4-oxo-3, 3-dimethyl-N-Boc-proline O BLP O O 10 %, pH 7. 2 H + Me-%, pH 7. 2 U-0 Y-Eo 0 H+ 30 C NBoc 98 % ee, Racemic ester 50 % conversion 10 mg of the racemic ester was suspended in 100 microliters of acetonitrile and was added to 900 mL of KPB buffer containing 10% Bacillus lentus protease (BLP). The reaction was stopped after 16 h, resulting in a 50% conversion and >98% ee of the acid product (2S)-4- oxo-3, 3-dimethyl-N-Boc-proline. Amano proleather FGF was another candidate, which was found to carry out this reaction with similar enatioselectivities and reactivity.
  • 2
  • [ 848444-88-2 ]
  • [ 478700-27-5 ]
 

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