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Chemical Structure| 480423-17-4 Chemical Structure| 480423-17-4

Structure of 480423-17-4

Chemical Structure| 480423-17-4

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Product Details of [ 480423-17-4 ]

CAS No. :480423-17-4
Formula : C14H10BrIN2O2S
M.W : 477.12
SMILES Code : IC(N1S(=O)(C2=CC=C(C)C=C2)=O)=CC3=C1N=CC=C3Br
MDL No. :MFCD11109388
InChI Key :KYVSBRIXLHDOBQ-UHFFFAOYSA-N
Pubchem ID :37818650

Safety of [ 480423-17-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of [ 480423-17-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 480423-17-4 ]

[ 480423-17-4 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 568577-88-8 ]
  • [ 480423-17-4 ]
  • 4-(4-(4-bromo-1-tosyl-1H-pyrrolo[2,3-b]pyridin-2-yl)phenyl)morpholine [ No CAS ]
YieldReaction ConditionsOperation in experiment
With bis-triphenylphosphine-palladium(II) chloride; sodium hydrogencarbonate; In water; N,N-dimethyl-formamide; at 100℃; for 1h; To stirring solution of 4-bromo-2-iodo-1 -tosyl-1 H-pyrrolo[2,3-b]pyridine (700 mg, 1.46 mmol), 4-(4-(4,4,5,5-tetramethyl-1 ,3,2-dioxaborolan-2- yl)phenyl)morpholine (636.4 mg, 2.20 mmol), and PdCI2(Ph3P)2 (1.3 mg, 0.14 mmol) in DMF (15 mL) were added solution of NaHC03 (370 mg, 4.40 mmol) in water (7 mL). The reaction was stirred at 100C for 1 h. The reaction mixture was diluted with dichloromethane and filtered through pad of silica gel washed with 10% MeOH/DCM (100 mL) and solvent was concentrated to dryness. The residue was purified by flash column chromatography on silica gel to afford 4-(4-(4-bromo-1 -tosyl-1 H-pyrrolo[2,3- b]pyridin-2-yl)phenyl)morpholine. LCMS-ESI+ (m/z): [M+H]+ calcd for C24H22BrN3 03S: 512.1 ; found: 512.10.
  • 2
  • [ 480423-17-4 ]
  • [ 819849-22-4 ]
  • C23H22BrN3O2S [ No CAS ]
  • 3
  • [ 480423-17-4 ]
  • [ 380430-57-9 ]
  • C21H18BrN3O4S2 [ No CAS ]
 

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[ 480423-17-4 ]

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Related Parent Nucleus of
[ 480423-17-4 ]

Other Aromatic Heterocycles

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