630-580-1088 sales@ambeed.com
Structure Search

List Search MOL Search Structure Search

0
Chemistry
Asymmetric Synthesis >>Chiral Building BlocksChiral Catalysts, Chiral Ligands and Chiral ReagentsChiral Resolution ReagentsBoronic acids/esters >>Aliphatic BoronsAromatic BoronsOther BoronsOxaborolesCatalysis Chemistry >>Achiral Crown LigandsC-H ActivationCarbon-Donor LigandsChiral Carbon LigandsChiral Crown LigandsChiral Olefin LigandsCross-CouplingCross-Coupling Using Transition Metal CatalystsDACH or Trost LigandsChemical Biology >>Conjugation Chemistry
GlycoscienceLinkers and CrosslinkersNucleic Acid ChemistryPEGylationPeptide ChemistryPhotolabile Protecting GroupHeterocyclic Building Blocks >>AcridinesAliphatic HeterocyclesAromatic HeterocyclesAzetidinesBenzimidazolesBenzisoxazolesBenzodioxansBenzofuransBenzothiazolesInorganic reagents >>Inorganic reagentOrganic Building Blocks >>Acid AnhydridesAcyl Chlorides
AlcoholsAldehydesAliphatic Chain HydrocarbonsAliphatic Cyclic HydrocarbonsAlkenesAlkylsAlkynesOrganometallic Reagents >>Grignard ReagentsOrganoarsenicOrganobismuthOrganoboronOrganogermaniumOrganolithiumOrganomercuryOrganosiliconOrganotinSpecialty Synthesis >>Enzyme-Mediated SynthesisFluorous SynthesisIonic Liquids
Solid Supported SynthesisStains and Dyes >>Acid DyesAzoic DyesBasic DyesDirect DyesDisperse DyesDye IntermediatesMordant DyesOil DyesOther Stains and DyesSynthetic Reagents >>Acids and BasesC-C Bond FormationC-X Bond Formation (Halogen)C-X Bond Formation (Non-Halogen)Chelation and Complexation CompoundsCondensation AgentsCouplingDehydrating ReagentsFluorination Reagent
Pharmaceutical Intermediates
Analgesics >>BenzhydrocodoneBicifadineCapsaicinCelecoxibDebio-0827DexamethasoneElagolix SodiumEsketamine HydrochlorideIbuprofen sodiumAnesthetics >>CiprofolEsketamine HydrochlorideFospropofol Fospropofol DisodiumLevobupivacaine RemimazolamRemimazolam BesilateRemimazolam besylateRopivacaineAnti-Addiction Agents >>Kakonein
Lofexidine HydrochlorideVarenicline Anti-inflammatory Agents >>ApremilastAsunaprevirATB-346 RelatedBalsalazide BaricitinibBencycloquidium BromideBudesonideCefiderocol Sulfate TosylateCeftaroline Fosamil AcetateAntibacterials >>AFN-1252 RelatedAlatrofloxacin Bedaquiline FumarateBesifloxacin BrilacidinCaspofungin AcetateCefiderocol Sulfate TosylateCefilavancinCeftaroline Fosamil
Anticonvulsants >>BrivaracetamCannabidiolEscitalopram OxalateEslicarbazepine Acetate RelatedFosphenytoinGabapentin EnacarbilJNJ-10234094LacosamideLevetiracetam RelatedAntidementia Agents >>Azeliragon RelatedDavunetideDonepezil HydrochlorideDonepezil RelatedEnsaculinFlorbetaben Flortaucipir F 18Flutemetamol IdalopirdineAntidepressants >>4-Chlorokynurenine
AgomelatineAgomelatine RelatedAllopregnanolone RelatedAmibegronAmitifadineAripiprazole RelatedBasimglurantBefloxatoneAntiemetics >>AprepitantAprepitant RelatedDolasetron RelatedDolasetron Mesylate HydrateFosaprepitant DimeglumineFosaprepitant RelatedOlanzapinePalonosetron RelatedPalonosetron HydrochlorideAntifungals >>Anidulafungin RelatedCabotegravirMore >>
Inhibitors/Agonists
ADC >>ADC AntibodyADC LinkerADC Linker with PayloadADC ToxinAntibody-Drug Conjugates (ADCs)Drug-Linker Conjugates for ADCAngiogenesis >>ALKBcr-AblBTKEGFRFAKFGFRFLT3HER2HIFAnti-infection >>3CLproAntibacterialAntibioticAntifungal
AntiparasiticAntiprotozoalAntiviralArenavirusBVDVApoptosis >>Apoptosis InducerBcl-2Bcl-6BRKc-Mycc-RETC/EBPCARDCaspaseAutophagy >>Atg4ATG4BATTECsAUTACsAutophagyBeclin1
FKBPLC3LRRK2Biochemical Reagent >>Cell Cycle >>AntifolateAPCAurora KinaseBUBCasein KinaseCdc25CDKChkCRISPR/Cas9Cytoskeleton >>ActinArp2/3 ComplexCYTHCytoplasmic dyneinDynaminFAKMore >>
Material Science
Aggregation-Induced Emission >>Other AIE BlocksTetraphenylethylene SeriesCOFs Linkers >>Aldehyde COFs LinkersAlkynyl COFs LinkersAmine COFs LinkersBoric COFs LinkersCyano COFs LinkersMultifunctional COFs linkersOther COFs linkersTriphene seriesElectronic Materials >>Battery MaterialsDye-Sensitized Solar Cell (DSSC) MaterialsElectronic MaterialLiquid Crystal (LC) MaterialsMolecular ConductorsOrganic Light-Emitting Diode (OLED) MaterialsOrganic Solar Cell (OPV) MaterialsOrganic Transistor (OFET) MaterialsPerovskite Solar Cell (PSC) MaterialsMagnetic Materials >>Magnetic Ionic LiquidsMagnetic MaterialMagnetic Metal Complexes
Organic Radicals Material Chemical Compounds >>Ligands for Functional Metal ComplexesLiquid Crystal (LC) Building BlocksPhthalocyanine Building BlocksPolymer and Macromolecule Semiconductor Building BlocksSmall Molecule Semiconductor Building BlocksSolubility Enhancing Reagents Supramolecular Host Materials MOF Ligands >>Carboxylic Acid MOF LigandsCarboxylic Acid Nitrogen-Containing Mixed MOF LigandsNitrogen-Containing MOF LigandsOther MOF ligandsNanomaterials >>Carbon NanomaterialsCeramic MembranesDendrimersGold NanoparticlesIron Oxide NanoparticlesMaterials by ApplicationMesoporous MaterialsMetals and Metal AlloysNano Minerals: NanoclaysOLED Materials >>Dopant
HostHTMOLED IntermediatesOther OLED related materialsOptical Materials >>Coumarin DyesCyanine and Squarylium DyesDCM DyesDipyrromethene DyesFluorescence MaterialsFluorescent ProbesHeat and Pressure Sensitive DyesNear-Infrared (NIR) DyesOrganic Non-Linear Optical (NLO) MaterialsOrganic Pigments >>Organic PigmentOther Materials >>Mateial OtherPolymer Science >>MonomersPolymer AdditivesPolymerization ReagentsPolymersResins
Contact Us
Home Cart 0 Sign in  
Chemistry
Organic Building Blocks
Aryls
1-(Bromomethyl)-3-chloro-5-fluorobenzene
Chemistry
Organic Building Blocks
Aryls
Bromides Chlorides Fluorinated Building Blocks Carboxylic Acids Benzene Compounds Benzyl Bromides

[ CAS No. 493024-39-8 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 493024-39-8
Chemical Structure| 493024-39-8
Structure of 493024-39-8 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

For Research Only 110K+ Compounds Competitive Price 1-2 Day Shipping

Quality Control of [ 493024-39-8 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 493024-39-8 ]

SDS Specification
Alternatived Products of [ 493024-39-8 ]

Product Details of [ 493024-39-8 ]

CAS No. :493024-39-8 MDL No. :MFCD03788472
Formula : C7H5BrClF Boiling Point : -
Linear Structure Formula :- InChI Key :PKSAHOPFPPAUOD-UHFFFAOYSA-N
M.W : 223.47 Pubchem ID :2734834
Synonyms :

Safety of [ 493024-39-8 ]

Signal Word:Danger Class:8
Precautionary Statements:P280-P305+P351+P338-P310 UN#:3265
Hazard Statements:H290-H314 Packing Group:Ⅱ
GHS Pictogram:

Application In Synthesis of [ 493024-39-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 493024-39-8 ]
  • Downstream synthetic route of [ 493024-39-8 ]

[ 493024-39-8 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 773837-37-9 ]
  • [ 493024-39-8 ]
  • [ 493038-93-0 ]
YieldReaction ConditionsOperation in experiment
100% With benzyltri(n-butyl)ammonium chloride; acetic acid In water; toluene at 20℃; for 4 h; To a solution of 3-chloro-5-fluorobenzyl bromide (58.23 g, 260 mmol) and acetic acid (5.35 mL, 93.6 mmol) in toluene (260 mL) was added dropwise an aqueous solution (195 mL) of sodium cyanide (48.57 g, 990 mmol) and tributylbenzylammonium chloride (5.68 g, 18.2 mmol). The reaction mixture was stirred at room temperature for 4 hr. The organic layer was separated, washed successively with water (200 mL) and saturated brine (200 mL), dried over anhydrous magnesium sulfate and concentrated under reduced pressure. The obtained residue was purified by basic silica gel column chromatography [eluent: hexane-ethyl acetate (4:1)] to give the title compound (44.89 g) as a brown oil (yield 100percent). 1H NMR (300 MHz, CDCl3) δ 3.74 (2H, s), 6.99 (1H, d, J = 8.7 Hz), 7.05-7.13 (1H, m), 7.15 (1H, s).
Reference： [1] Patent: EP2530078, 2012, A1, . Location in patent: Page/Page column 118

Tags: 493024-39-8 synthesis path| 493024-39-8 SDS| 493024-39-8 COA| 493024-39-8 purity| 493024-39-8 application| 493024-39-8 NMR| 493024-39-8 COA| 493024-39-8 structure

Same Skeleton Products
Related Products
Historical Records

Related Functional Groups of
[ 493024-39-8 ]

Fluorinated Building Blocks

Chemical Structure| 206362-80-3

[ 206362-80-3 ]

4-(Bromomethyl)-1-chloro-2-fluorobenzene

Similarity: 0.89

Chemical Structure| 192702-01-5

[ 192702-01-5 ]

4-(Bromomethyl)-2-chloro-1-fluorobenzene

Similarity: 0.89

Chemical Structure| 1400991-56-1

[ 1400991-56-1 ]

5-(Bromomethyl)-2-chloro-1,3-difluorobenzene

Similarity: 0.86

Chemical Structure| 206362-80-3

[ 206362-80-3 ]

4-(Bromomethyl)-1-chloro-2-fluorobenzene

Similarity: 0.89

Chemical Structure| 192702-01-5

[ 192702-01-5 ]

4-(Bromomethyl)-2-chloro-1-fluorobenzene

Similarity: 0.89

Aryls

Chemical Structure| 206362-80-3

[ 206362-80-3 ]

4-(Bromomethyl)-1-chloro-2-fluorobenzene

Similarity: 0.89

Chemical Structure| 192702-01-5

[ 192702-01-5 ]

4-(Bromomethyl)-2-chloro-1-fluorobenzene

Similarity: 0.89

Chemical Structure| 1400991-56-1

[ 1400991-56-1 ]

5-(Bromomethyl)-2-chloro-1,3-difluorobenzene

Similarity: 0.86

Chemical Structure| 206362-80-3

[ 206362-80-3 ]

4-(Bromomethyl)-1-chloro-2-fluorobenzene

Similarity: 0.89

Chemical Structure| 192702-01-5

[ 192702-01-5 ]

4-(Bromomethyl)-2-chloro-1-fluorobenzene

Similarity: 0.89

Bromides

Chemical Structure| 206362-80-3

[ 206362-80-3 ]

4-(Bromomethyl)-1-chloro-2-fluorobenzene

Similarity: 0.89

Chemical Structure| 192702-01-5

[ 192702-01-5 ]

4-(Bromomethyl)-2-chloro-1-fluorobenzene

Similarity: 0.89

Chemical Structure| 1400991-56-1

[ 1400991-56-1 ]

5-(Bromomethyl)-2-chloro-1,3-difluorobenzene

Similarity: 0.86

Chemical Structure| 206362-80-3

[ 206362-80-3 ]

4-(Bromomethyl)-1-chloro-2-fluorobenzene

Similarity: 0.89

Chemical Structure| 192702-01-5

[ 192702-01-5 ]

4-(Bromomethyl)-2-chloro-1-fluorobenzene

Similarity: 0.89

Chlorides

Chemical Structure| 206362-80-3

[ 206362-80-3 ]

4-(Bromomethyl)-1-chloro-2-fluorobenzene

Similarity: 0.89

Chemical Structure| 192702-01-5

[ 192702-01-5 ]

4-(Bromomethyl)-2-chloro-1-fluorobenzene

Similarity: 0.89

Chemical Structure| 1400991-56-1

[ 1400991-56-1 ]

5-(Bromomethyl)-2-chloro-1,3-difluorobenzene

Similarity: 0.86

Chemical Structure| 206362-80-3

[ 206362-80-3 ]

4-(Bromomethyl)-1-chloro-2-fluorobenzene

Similarity: 0.89

Chemical Structure| 192702-01-5

[ 192702-01-5 ]

4-(Bromomethyl)-2-chloro-1-fluorobenzene

Similarity: 0.89

Benzyl Bromides

Chemical Structure| 206362-80-3

[ 206362-80-3 ]

4-(Bromomethyl)-1-chloro-2-fluorobenzene

Similarity: 0.89

Chemical Structure| 192702-01-5

[ 192702-01-5 ]

4-(Bromomethyl)-2-chloro-1-fluorobenzene

Similarity: 0.89

Chemical Structure| 1400991-56-1

[ 1400991-56-1 ]

5-(Bromomethyl)-2-chloro-1,3-difluorobenzene

Similarity: 0.86

Chemical Structure| 206362-80-3

[ 206362-80-3 ]

4-(Bromomethyl)-1-chloro-2-fluorobenzene

Similarity: 0.89

Chemical Structure| 192702-01-5

[ 192702-01-5 ]

4-(Bromomethyl)-2-chloro-1-fluorobenzene

Similarity: 0.89