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Chemical Structure| 50609-15-9 Chemical Structure| 50609-15-9

Structure of 50609-15-9

Chemical Structure| 50609-15-9

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Product Details of [ 50609-15-9 ]

CAS No. :50609-15-9
Formula : C6H8N4O2
M.W : 168.15
SMILES Code : CC(NC1=C(N)N=CNC1=O)=O
MDL No. :MFCD02091123

Safety of [ 50609-15-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 50609-15-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 50609-15-9 ]

[ 50609-15-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 50609-15-9 ]
  • [ 92001-52-0 ]
YieldReaction ConditionsOperation in experiment
6% Step 1: 6-chloro-8-methyl-9H-purine A solution of N-(4-amino-6-oxo-1,6-dihydropyrimidin-5-yl)acetamide (330 mg, 1.92 mmol, 1.00 equiv, 98%) in phosphorus oxychloride (5 mL) was refluxed overnight. The resulting mixture was concentrated under vacuum. The residue was redissolved in 10 mL of ethyl acetate, washed with 10 mL of saturated aqueous sodium bicarbonate solution, 1×10 mL of water and 1×10 mL of brine. The organic layer was dried over anhydrous sodium sulfate and concentrated under vacuum to give 20 mg (6%) of 6-chloro-8-methyl-9H-purine as a yellow solid.
 

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