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Chemical Structure| 50850-16-3 Chemical Structure| 50850-16-3

Structure of 50850-16-3

Chemical Structure| 50850-16-3

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Product Details of [ 50850-16-3 ]

CAS No. :50850-16-3
Formula : C7H11N3
M.W : 137.18
SMILES Code : NC1=NC(C)=CC(C)=C1N
MDL No. :MFCD08436406
InChI Key :KOFVAOOMAVAGHM-UHFFFAOYSA-N
Pubchem ID :11029902

Safety of [ 50850-16-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H312-H332
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P330-P362-P403+P233-P501

Application In Synthesis of [ 50850-16-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 50850-16-3 ]

[ 50850-16-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 50850-16-3 ]
  • [ 28697-11-2 ]
  • C21H24N4O2 [ No CAS ]
YieldReaction ConditionsOperation in experiment
16% Example 82 Preparation of Intermediate 84 [0729] [0730] (S)-(-)-1-(carbobenzyloxy)-2-piperidinecarboxylic acid (500 mg, 1.9 mmol) and HATU (1.16 g, 3 mmol) were dissolved in anhydrous DMF (1 mL). After activation for 1 hour, 2,3-diamino-4,6-dimethylpyridine (253 mg, 1.9 mmol) and triethylamine (0.53 mL, 3.80 mmol) were added. The reaction mixture was stirred under nitrogen for 2 hours. The solvents were removed under reduced pressure and the residue was treated with acetic acid (2.5 mL) and heated at 170 C. The solvent was evaporated under reduced pressure and the residue was purified via silica gel column chromatography (0-100% ethyl acetate in hexanes) to provide intermediate 84. (Yield 111 mg, 16%). [0731] LCMS m/z [M+H]+ C21H24N4O2 requires: 365.19. Found 365.12 [0732] HPLC Tr (min), purity %: 2.47, 98%.
 

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[ 50850-16-3 ]

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Related Parent Nucleus of
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