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Chemical Structure| 515160-72-2 Chemical Structure| 515160-72-2

Structure of 515160-72-2

Chemical Structure| 515160-72-2

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Product Details of [ 515160-72-2 ]

CAS No. :515160-72-2
Formula : C13H20N2O2
M.W : 236.31
SMILES Code : COCCOC1=CC=C(N2CCNCC2)C=C1
MDL No. :MFCD08437661
InChI Key :NTVPCGYHMHFTNW-UHFFFAOYSA-N
Pubchem ID :22024914

Safety of [ 515160-72-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 515160-72-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 515160-72-2 ]

[ 515160-72-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 158690-56-3 ]
  • [ 515160-72-2 ]
  • tert-butyl (2-(4-(4-(2-methoxyethoxy)phenyl)piperazin-1-yl)ethyl)carbamate [ No CAS ]
YieldReaction ConditionsOperation in experiment
74.8% With potassium carbonate; In acetonitrile; at 80℃; for 6h; 2-((tert-butoxycarbonyl) amino) ethyl 4-methylbenzenesulfonate (700 mg, 2.2 mmol),1- [4- (2-methoxyethoxy) phenyl] piperazine (630mg, 2.7mmol),Potassium carbonate (460mg, 3.3mmol) and acetonitrile (10mL)Add to 100mL single-necked round bottom flask,The temperature was raised to 80 C and reacted for 6 hours.Stop the reaction,After cooling to room temperature,Spin dry under reduced pressure to remove most of the solvent,Add water (20mL) and dichloromethane (30mL),Liquid separation,Collect the organic phase,Spin dry under reduced pressure,Column chromatography separation and purification (dichloromethane / methanol (v / v) = 50/1) gave the title compound as a white solid (0.63g, 74.8%).
 

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