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Chemical Structure| 52103-12-5 Chemical Structure| 52103-12-5

Structure of 52103-12-5

Chemical Structure| 52103-12-5

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Product Details of [ 52103-12-5 ]

CAS No. :52103-12-5
Formula : C8H15IO2
M.W : 270.11
SMILES Code : ICCCOC1CCCCO1
MDL No. :MFCD25964111

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Application In Synthesis of [ 52103-12-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 52103-12-5 ]

[ 52103-12-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 15469-97-3 ]
  • [ 52103-12-5 ]
  • 3-(1-Triphenylmethylimidazol-2-yl)-1-(tetrahydropyran-2-yloxy)propane [ No CAS ]
YieldReaction ConditionsOperation in experiment
With n-butyllithium; In tetrahydrofuran; hexane; A. 3-(1-Triphenylmethylimidazol-2-yl)-1-(tetrahydropyran-2-yloxy)propane A solution of 310 mg (1 mmol) of 1-triphenylmethylimidazole (K H. Buchel et al.; Drugs Made in Germany, 1972, 15, 77) in 12 ml of dry THF is cooled to 0° under nitrogen and treated with 0.647 ml (1.1 mmol) of 1.7 M solution of n-BuLi in hexane. The solution is stirred at room temperature for 1 hour, then recooled to 0° and treated with 405 mg (1.5 mmol) of 1-iodo-3-(tetrahydropyran-2-yloxy)propane dissolved in 2 ml of dry THF. The reaction mixture is allowed to warm to room temperature overnight, then poured into water and extracted with ethyl acetate. The organic extract is rinsed with brine and dried (MgSO4). Removal of solvents in vacuo affords the title A compound.
 

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