Home Cart Sign in  
Chemical Structure| 522600-26-6 Chemical Structure| 522600-26-6

Structure of 522600-26-6

Chemical Structure| 522600-26-6

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 522600-26-6 ]

CAS No. :522600-26-6
Formula : C14H6Cl2F3N3O
M.W : 360.12
SMILES Code : O=C(Cl)C1=NN2C(C(F)(F)F)=CC(C3=CC=C(Cl)C=C3)=NC2=C1
MDL No. :MFCD03421549

Safety of [ 522600-26-6 ]

Application In Synthesis of [ 522600-26-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 522600-26-6 ]

[ 522600-26-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 522600-26-6 ]
  • [ 312922-12-6 ]
  • [ 35216-39-8 ]
  • [ 522599-89-9 ]
YieldReaction ConditionsOperation in experiment
93% In pyridine; acetonitrile; Example 6 Preparation of 5-(4-Chloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (3-methanesulfonyl-phenyl)-amide 5-(4-Chloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride (0.100 g, 0.277 mmol) (prepared from 5-(4-chloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid using standard procedures, e.g.; thionyl chloride) was added to a solution of <strong>[35216-39-8]3-methanesulfonyl-phenylamine</strong> (0.052 mL, 0.304 mmol) in acetonitrile (10 mL) containing pyridine (0.067 mL, 0.831 mmol). The reaction mixture was stirred overnight at room temperature, diluted with ethyl acetate (25 mL) and washed with 1M hydrochloric acid (50 mL). The organic layer was collected, concentrated under reduced pressure and the crude product was purified by column chromatography on silica gel to give 5-(4-chloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (3-methanesulfonyl-phenyl)-amide (0.128 g, 93%).
 

Historical Records

Technical Information

Categories