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Chemical Structure| 52505-48-3 Chemical Structure| 52505-48-3

Structure of 52505-48-3

Chemical Structure| 52505-48-3

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Product Details of [ 52505-48-3 ]

CAS No. :52505-48-3
Formula : C14H10N2OS
M.W : 254.31
SMILES Code : O=C(C1=C(N)C2=CC=CN=C2S1)C3=CC=CC=C3

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Application In Synthesis of [ 52505-48-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 52505-48-3 ]

[ 52505-48-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 14401-72-0 ]
  • [ 52505-48-3 ]
  • 2-(3,5-dichlorophenyl)-4-phenylthieno[3,2-b: 5,4-b'] [ No CAS ]
YieldReaction ConditionsOperation in experiment
38% With sulfuric acid; acetic acid; at 120℃; for 65h;Inert atmosphere; Under an argon stream, 3-amino-2-benzoylthieno [2,3-b] pyridine (2.54 g), and <strong>[14401-72-0]3,5-dichloroacetophenone</strong> (3.12 g) was added to acetic acid (20 mL), concentrated sulfuric acid (2.6 mL) was further added, and the mixture was stirred with heating at 120 C. for 65 hours. The reaction mixture was allowed to cool to room temperature and then water was added. The precipitated solid was washed with water, suspended in methanol, and then a saturated aqueous sodium hydrogen carbonate solution was added. After heating and stirring the mixture at 60 C., insoluble matter was filtered off. By purifying the filtrate by column chromatography (developing solvent: chloroform), the objective A white powder of 2- (3,5-dichlorophenyl) -4-phenylthieno [3,2-b: 5,3-b '] dipyridine (Yield 1.54 g, yield 38%).
 

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