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Chemical Structure| 52755-67-6 Chemical Structure| 52755-67-6

Structure of 52755-67-6

Chemical Structure| 52755-67-6

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Product Details of [ 52755-67-6 ]

CAS No. :52755-67-6
Formula : C10H9NO2
M.W : 175.18
SMILES Code : O=C1C(C2=CC=CC=C2)=NC(C)O1

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Application In Synthesis of [ 52755-67-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 52755-67-6 ]

[ 52755-67-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 52755-67-6 ]
  • [ 574-12-9 ]
  • (R)-4-methyl-((S)-4-oxochroman-2-yl)-2-phenyl-1,3-oxazol-5(4H)-one [ No CAS ]
  • (S)-4-methyl-((R)-4-oxochroman-2-yl)-2-phenyl-1,3-oxazol-5(4H)-one [ No CAS ]
  • C19H15NO4 [ No CAS ]
YieldReaction ConditionsOperation in experiment
With C31H32N4O4; In tetrahydrofuran; at 20℃; for 24h;Sealed tube; General procedure: An ordinary screw-cap vial was charged with a magnetic stirring bar, the corresponding chromone-3-carboxylic acid 2 (0.1 mmol, 1 equiv), THF (0.2 mL), catalyst 9e (0.02mmol, 0.2 equiv) and thecorresponding azlactone 1 (0.1 mmol, 1 equiv). The reaction mixture was stirred at room temperatureand monitored by 1H NMR spectroscopy. After complete consumption of the carboxylic acid 2 themixture was directly subjected to FC on silica gel (hexane:ethyl acetate 15:1 or 10:1) to afford pureproduct 3.
 

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