Alternatived Products of [ 5298-50-0 ]
Product Details of [ 5298-50-0 ]
CAS No. : | 5298-50-0 |
MDL No. : | MFCD15142956 |
Formula : |
C6H7Cl2N3
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
192.05
|
Pubchem ID : | - |
Synonyms : |
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Safety of [ 5298-50-0 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 5298-50-0 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 5298-50-0 ]
- 1
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[ 37454-51-6 ]
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[ 5298-50-0 ]
Yield | Reaction Conditions | Operation in experiment |
68% |
With trichlorophosphate; for 2.0h;Reflux; |
A solution of the aforementioned intermediate 2 (400 mg, 2.58 mmol) in POd3 (10 mL) was heated to reflux and stirred for 2 h. The mixture was cooled to room temperature and poured slowly into ice-water (100 mL). The aqueous phase was extracted with DCM (50 mL x 3). The organic layers were combined and dried over Na2SO4. The Na2SO4 was removed by filtration, and the volatileswere removed under reduced pressure, and the residue was purified by flashchromatography using a mixture of DCM and THF to give 2,4-dichloro-N,N-dimethylpyrimidin-5-amine 3 (340 mg, 68%) as a yellow oil. LRMS (M + H)m/z: calcd 192.00; found 192. |