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Chemical Structure| 530-52-9 Chemical Structure| 530-52-9

Structure of 530-52-9

Chemical Structure| 530-52-9

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Product Details of [ 530-52-9 ]

CAS No. :530-52-9
Formula : C11H7NO2
M.W : 185.18
SMILES Code : O=C1C2=C(OC=C2)NC3=C1C=CC=C3

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Application In Synthesis of [ 530-52-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 530-52-9 ]

[ 530-52-9 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 186581-53-3 ]
  • [ 530-52-9 ]
  • [ 484-74-2 ]
  • [ 484-29-7 ]
  • 2
  • [ 484-29-7 ]
  • [ 530-52-9 ]
YieldReaction ConditionsOperation in experiment
91% With hydrogen bromide; In water; acetic acid; for 8.0h;Heating / reflux; A mixture of <strong>[484-29-7]4-methoxyfuro[2,3-b]quinoline</strong> (compound 1; 0.20 g, 1 mmol), 48% HBr (10 ml), and AcOH (20 ml) was refluxed for 8 h. After cooling, the mixture was poured into an ice-cold sat. NaHCO3 solution (60 ml), and extracted with AcOEt (3×60 ml). The AcOEt extracts were combined, washed with H2O, dried on MgSO4, and evaporated to yield a residual solid, which was purified by flash column chromatography (FC; silica gel; AcOEt). The proper fractions were combined and evaporated to obtain compound 2 (0.17 g, 91%). Detected Properties of the Title Compound: M.p. 236-237 C. 1H-NMR (200 MHz, DMSO): 7.06 (d,J=2.4, H-C(3)) 7.29 (m,H-C(6)); 7.56-7.68 (m,H-C(2), H-C(7), H-C(8)); 8.28 (d,J)=7.6, H-C(5)). 13C-NMR (50 MHz, DMSO): 104.85; 105.84; 121.60; 122.12; 123.08; 124.60; 130.06; 140.04; 142.53; 160.70; 166.69.
  • 3
  • [ 530-52-9 ]
  • [ 484-29-7 ]
 

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