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Chemical Structure| 53348-92-8 Chemical Structure| 53348-92-8

Structure of 53348-92-8

Chemical Structure| 53348-92-8

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Product Details of [ 53348-92-8 ]

CAS No. :53348-92-8
Formula : C9H7NO2
M.W : 161.16
SMILES Code : O=C1C=C(N)C2=C(O1)C=CC=C2
MDL No. :MFCD00033697

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Application In Synthesis of [ 53348-92-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 53348-92-8 ]

[ 53348-92-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 53348-92-8 ]
  • [ 31686-94-9 ]
  • ethyl 4-(4-fluorophenyl)-5-oxo-5H-chromeno[4,3-b]pyridine-2-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
0.26 g In propan-1-ol; for 11h;Reflux; General procedure: A mixture of 4-hydroxy coumarin (1 mmol) andammonia solution (28-30%, 5 mmol) in n-PrOH (5 mL) was refluxed for 1h. Then, ethyl 2,4-dioxo-4-arylbutnote (1 mmol) was added and the reaction was contnued at reflux temperature for another 11 h. After this time, the reactionwas cooled down to room temperature. The precipitate wasfiltered and purified by column chromatography (petroleumether/ethyl acetate(8 :2).
 

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