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Chemical Structure| 54314-85-1 Chemical Structure| 54314-85-1

Structure of 54314-85-1

Chemical Structure| 54314-85-1

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Product Details of [ 54314-85-1 ]

CAS No. :54314-85-1
Formula : C28H28BrOP
M.W : 491.40
SMILES Code : C1([P+](C2=CC=CC=C2)(CCCOCC3=CC=CC=C3)C4=CC=CC=C4)=CC=CC=C1.[Br-]
MDL No. :MFCD00191781
InChI Key :DWYCJWXMZGVGJV-UHFFFAOYSA-M
Pubchem ID :10929077

Safety of [ 54314-85-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 54314-85-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 54314-85-1 ]

[ 54314-85-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 13417-49-7 ]
  • [ 54314-85-1 ]
  • (Z)-5-(4-[(phenylmethyl)oxy]-1-buten-1-yl)-3,6-dihydro-2H-pyran [ No CAS ]
  • (E)-5-(4-[(phenylmethyl)oxy]-1-buten-1-yl)-3,6-dihydro-2H-pyran [ No CAS ]
YieldReaction ConditionsOperation in experiment
Intermediate 141 : 5-{4-r(Phenylmethyl)oxyl-1-buten-1-yl)-3,6-dihvdro-2H-pyranTo a suspension of (3-benzyloxypropyl)triphenylphosphonium bromide (9.90 g) in dry tetrahydrofuran (30.5 ml) at -15C was added butyllithium (8.06 ml, 2.5M in hexanes) dropwise to give a dark orange solution. The reaction temperature was increased to O0C and stirring was continued for 30 minutes. A solution of 5,6-dihydro-2H-pyran-3- carbaldehyde (2.26 g) in dry tetrahydrofuran (3 ml) was added dropwise at O0C. The reaction mixture was stirred at room temperature for 20 hours. The reaction mixture was filtered through celite and washed with diethyl ether. The filtrate was concentrated in vacuo to give an orange oil. The product was purified by silica chromatography using a gradient elution of 0-25% ethyl acetate/cyclohexane to afford the title compound as a colourless oil (2.04 g).1H-NMR (CDCI3): Mixture of cis and trans delta 7.40-7.27 (5H, m), 6.02 (0.60H, d), 5.76 (1.36H, m), 5.49-5.37 (1 H, m), 4.53 (2H, m), 4.29 (1.23H), 4.22 (0.74H, m), 3.77 (2H, t), 3.51 (2H, m), 2.52 (0.78H, m), 2.40 (1.29H, m), 2.24 (2H, m).
 

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