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Chemical Structure| 55001-09-7 Chemical Structure| 55001-09-7

Structure of 55001-09-7

Chemical Structure| 55001-09-7

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Product Details of [ 55001-09-7 ]

CAS No. :55001-09-7
Formula : C11H14O3
M.W : 194.23
SMILES Code : O=C(OC)CCC1=CC=CC=C1OC
MDL No. :MFCD12031733

Safety of [ 55001-09-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H319
Precautionary Statements:P305+P351+P338

Application In Synthesis of [ 55001-09-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 55001-09-7 ]

[ 55001-09-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 55001-09-7 ]
  • [ 10493-37-5 ]
YieldReaction ConditionsOperation in experiment
74.0% With lithium aluminium tetrahydride; In tetrahydrofuran; at 20℃; for 2.5h; General procedure: A mixture of Lithium aluminum hydride (9.5 g, 0.250 mol), dry THF(250 mL), to it add substituted dihydrocinnamic acid methyl ester (3ae,0.127 mol), in THF (50 mL) was added slowly drop wise during30 min. After completion of addition the reaction mixture was stirredfor 2 h at rt, after completion of reaction as monitored by TLC hexane/ethyl acetate (8:2), the reaction mixture was poured in water (200 mL),acidified with 5 N HCl, extract with chloroform (2×400 mL), extractwas wash with water, brine solution, dried over Na2SO4 and concentrated.The crude residue was subjected to column chromatographyon silica gel, column was eluted with hexane/ethyl acetate mixtures,pure compound was eluted in ethyl acetate in hexane, 10%/90% (v/v)which was monitored by TLC, pure fractions were combined and concentratedto obtained 3-(substituted phenyl)- propan-1-ol as oily compoundswith yields of 73-77%.
  • 2
  • [ 495-78-3 ]
  • [ 77-78-1 ]
  • [ 55001-09-7 ]
 

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