Home Cart Sign in  
Chemical Structure| 55160-66-2 Chemical Structure| 55160-66-2

Structure of 55160-66-2

Chemical Structure| 55160-66-2

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 55160-66-2 ]

CAS No. :55160-66-2
Formula : C6H12ClNO2S
M.W : 197.68
SMILES Code : ClCCN1CCS(CC1)(=O)=O

Safety of [ 55160-66-2 ]

Application In Synthesis of [ 55160-66-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 55160-66-2 ]

[ 55160-66-2 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 55160-66-2 ]
  • [ 22717-55-1 ]
  • methyl 4-chloro-2-(2-(1,1-dioxidothiomorpholino)ethoxy)benzoate [ No CAS ]
YieldReaction ConditionsOperation in experiment
25% With tetrabutylammomium bromide; potassium carbonate; In acetone; for 16h;Reflux; To a stirred solution of <strong>[22717-55-1]methyl 4-chloro-2-hydroxybenzoate</strong> (step 1, 3.0 g, 16.078mmol, 1.0 eq) in acetone (60 mL) was added K2C03 (11.11 g, 80.39 mmol, 5.0 eq) followedby 4-(2-chloroethyl)thiomorpholine 1,1-dioxide (3.183 g, 16.078 mmol, 1.0 eq) and tetra-n-5 butylammonium bromide (1.035 g, 3.215 mmol, 0.2 eq). The reaction mixture was heated toreflux for 16 hours. After completion of the reaction (monitored by TLC), the reactionmixture was evaporated under reduced pressure, diluted with water (200 mL) and extractedwith ethyl acetate (2xl00 mL). The combined organic extracts were washed with water (100mL), dried over sodium sulfate, filtered and evaporated under reduced pressure. The residue10 was purified by silica gel column chromatography by using 0-2% methanol indichloromethane gradient. The fractions containing the expected product were combined andconcentrated under reduced pressure to obtain the title compound ( 1.4 g, yield: 25%) as aliquid. 1H NMR (300 MHz, CDCh): 8 ppm 7.77 (d, J = 8.1 Hz, lH), 7.02-6.93 (m, 2H), 4.14(t, J = 5.1 Hz, 2H), 3.85 (s, 3H), 3.26-3.20 (m, 4H), 3.10-3.01 (m, 6H); ESI-MS: m/z 348.1015 (M+Ht
  • 2
  • [ 55160-66-2 ]
  • [ 22717-55-1 ]
  • 4-chloro-2-(2-(1,1-dioxidothiomorpholino)ethoxy)benzoic acid [ No CAS ]
 

Historical Records

Technical Information

Categories