Home Cart 0 Sign in  

[ CAS No. 5565-72-0 ]

{[proInfo.proName]} ,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 5565-72-0
Chemical Structure| 5565-72-0
Structure of 5565-72-0 * Storage: {[proInfo.prStorage]}

Quality Control of [ 5565-72-0 ]

Related Doc. of [ 5565-72-0 ]

SDS
Alternatived Products of [ 5565-72-0 ]
Alternatived Products of [ 5565-72-0 ]

Product Details of [ 5565-72-0 ]

CAS No. :5565-72-0 MDL No. :MFCD00085145
Formula : C8H5N3O3 Boiling Point : -
Linear Structure Formula :- InChI Key :-
M.W :191.14 g/mol Pubchem ID :-
Synonyms :

Safety of [ 5565-72-0 ]

Signal Word:Warning Class:
Precautionary Statements:P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362 UN#:
Hazard Statements:H315-H319 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 5565-72-0 ]

  • Downstream synthetic route of [ 5565-72-0 ]

[ 5565-72-0 ] Synthesis Path-Downstream   1~14

  • 1
  • [ 103274-29-9 ]
  • [ 5565-72-0 ]
  • 2
  • [ 5565-72-0 ]
  • [ 35219-13-7 ]
  • [ 5378-35-8 ]
YieldReaction ConditionsOperation in experiment
With hydrogen In methanol for 1h; Ambient temperature;
  • 3
  • [ 122-51-0 ]
  • [ 618-94-0 ]
  • [ 5565-72-0 ]
YieldReaction ConditionsOperation in experiment
88% With sulfuric acid; silica gel at 20℃;
78.9% at 100℃; for 3h; 4.A Step A: 2-(3-nitrophenyl)-1,3,4-oxadiazole 2-(3-nitrophenyl)-l,3,4-oxadiazole. A mixture of 3-nitrobenzohydrazide (1.8 g, 10 mmol), triethoxymethane (5 mL) and 0.1 mL CH(OEt)3 was stirred at 100 °C for 3 hr. The mixture was concentrated to small volume and cooled down to give a colorless crystal. The solid was collected by filtration and dried under vacuum to afford the desired compound (1.5 g, 78.9% yield). MS: 192.2 (M+l)+.
In xylene for 6.7h; Heating;
4.A Step A: Step A: 2-(3-nitrophenyl)-1,3,4-oxadiazole A mixture of 3-nitrobenzohydrazide (1.8 g, 10 mmol), triethoxymethane (5 mL) and 0.1 mL CH(OEt)3 was stirred at 100° C. for 3 hr. The mixture was concentrated to small volume and cooled down to give a colorless crystal. The solid was collected by filtration and dried under vacuum to afford the desired compound (1.5 g, 78.9% yield). MS: 192.2 (M+1)+.

  • 4
  • [ 138267-85-3 ]
  • [ 5565-72-0 ]
YieldReaction ConditionsOperation in experiment
100% In benzene for 0.0833333h; Ambient temperature;
85% With Chloroacetic anhydride In toluene for 0.5h;
YieldReaction ConditionsOperation in experiment
Hydrazid, RC(OEt)3;
entspr. Benzhydrazid, RC(OEt)3;
  • 6
  • [ 618-94-0 ]
  • [ 149-73-5 ]
  • [ 5565-72-0 ]
YieldReaction ConditionsOperation in experiment
92% With Al3+-K10 montmorillonite clay; In neat (no solvent); at 55℃; for 0.25h;Microwave irradiation; General procedure: A 5 mL microwave vial was charged with acidhydrazide (100 mg, 1 eq), trimethyl orthoester (2 eq) and Al3+-K10 clay (75 mg). The resulting mixture was kept under microwave irradiation maintaining the temperature at 55 C for 15 min (Microwave irradiations were performed on CEM-discover model No. 908010). The reaction was monitored by TLC. After completion of the reaction, reaction mixture was diluted with ethyl acetate stirred well, filtered, washed well with ethyl acetate. Filtrate was evaporated under reduced pressure to obtain highly pure product. In some cases, products were purified by column chromatography using 60-120 mesh silica with 20-100 % ethyl acetate in pet ether as eluting solvents. The catalyst recovered by filtration was reused for another 5 more times.
  • 7
  • [ 126175-90-4 ]
  • [ 5565-72-0 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: 80 percent / 0.33 h / Heating 2: 85 percent / chloroacetic anhydride / toluene / 0.5 h
  • 9
  • [ 5565-72-0 ]
  • [ 6336-70-5 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1: H2 / Pd-C / methanol / 1 h / 760 Torr / Ambient temperature 2: Py / 4 h / 95 °C 3: aq. NaOH / Heating
  • 10
  • [ 5565-72-0 ]
  • [ 96432-49-4 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1: H2 / Pd-C / methanol / 1 h / 760 Torr / Ambient temperature 2: Py / 4 h / 95 °C 3: aq. NaOH / Heating
  • 11
  • [ 5565-72-0 ]
  • [ 92150-28-2 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1: H2 / Pd-C / methanol / 1 h / 760 Torr / Ambient temperature 2: benzene / Ambient temperature 3: H2 / Pd-C / methanol / 1 h / 760 Torr / Ambient temperature
  • 12
  • [ 5565-72-0 ]
  • [ 92906-13-3 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: H2 / Pd-C / methanol / 1 h / 760 Torr / Ambient temperature 2: benzene / Ambient temperature
  • 13
  • [ 5565-72-0 ]
  • [ 92906-14-4 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: H2 / Pd-C / methanol / 1 h / 760 Torr / Ambient temperature 2: benzene / Ambient temperature
  • 14
  • [ 5565-72-0 ]
  • [ 1071691-56-9 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: H2 / Pd-C / methanol / 1 h / 760 Torr / Ambient temperature 2: Py / 4 h / 95 °C
Historical Records

Related Functional Groups of
[ 5565-72-0 ]

Nitroes

Chemical Structure| 122733-39-5

[ 122733-39-5 ]

2-Methyl-5-(3-nitrophenyl)-1,3,4-oxadiazole

Similarity: 0.98

Chemical Structure| 311313-27-6

[ 311313-27-6 ]

2-(3-Nitrophenyl)-5-(p-tolyl)-1,3,4-oxadiazole

Similarity: 0.98

Chemical Structure| 1874-38-0

[ 1874-38-0 ]

2-(3-Nitrophenyl)-5-phenyl-1,3,4-oxadiazole

Similarity: 0.98

Chemical Structure| 122733-39-5

[ 122733-39-5 ]

2-Methyl-5-(3-nitrophenyl)-1,3,4-oxadiazole

Similarity: 0.98

Chemical Structure| 311313-27-6

[ 311313-27-6 ]

2-(3-Nitrophenyl)-5-(p-tolyl)-1,3,4-oxadiazole

Similarity: 0.98

Aryls

Chemical Structure| 122733-39-5

[ 122733-39-5 ]

2-Methyl-5-(3-nitrophenyl)-1,3,4-oxadiazole

Similarity: 0.98

Chemical Structure| 311313-27-6

[ 311313-27-6 ]

2-(3-Nitrophenyl)-5-(p-tolyl)-1,3,4-oxadiazole

Similarity: 0.98

Chemical Structure| 1874-38-0

[ 1874-38-0 ]

2-(3-Nitrophenyl)-5-phenyl-1,3,4-oxadiazole

Similarity: 0.98

Chemical Structure| 122733-39-5

[ 122733-39-5 ]

2-Methyl-5-(3-nitrophenyl)-1,3,4-oxadiazole

Similarity: 0.98

Chemical Structure| 311313-27-6

[ 311313-27-6 ]

2-(3-Nitrophenyl)-5-(p-tolyl)-1,3,4-oxadiazole

Similarity: 0.98

Related Parent Nucleus of
[ 5565-72-0 ]

Oxadiazoles

Chemical Structure| 122733-39-5

[ 122733-39-5 ]

2-Methyl-5-(3-nitrophenyl)-1,3,4-oxadiazole

Similarity: 0.98

Chemical Structure| 311313-27-6

[ 311313-27-6 ]

2-(3-Nitrophenyl)-5-(p-tolyl)-1,3,4-oxadiazole

Similarity: 0.98

Chemical Structure| 1874-38-0

[ 1874-38-0 ]

2-(3-Nitrophenyl)-5-phenyl-1,3,4-oxadiazole

Similarity: 0.98

Chemical Structure| 122733-39-5

[ 122733-39-5 ]

2-Methyl-5-(3-nitrophenyl)-1,3,4-oxadiazole

Similarity: 0.98

Chemical Structure| 311313-27-6

[ 311313-27-6 ]

2-(3-Nitrophenyl)-5-(p-tolyl)-1,3,4-oxadiazole

Similarity: 0.98