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Chemical Structure| 56147-30-9 Chemical Structure| 56147-30-9

Structure of 56147-30-9

Chemical Structure| 56147-30-9

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Product Details of [ 56147-30-9 ]

CAS No. :56147-30-9
Formula : C12H16O
M.W : 176.26
SMILES Code : CCC(C1=CC=C(CCC)C=C1)=O
MDL No. :MFCD01993684

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Application In Synthesis of [ 56147-30-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 56147-30-9 ]

[ 56147-30-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 56147-30-9 ]
  • [ 25150-61-2 ]
  • 4'-Propyl-2-methyl-3-pyrrolidinopropiophenone [ No CAS ]
YieldReaction ConditionsOperation in experiment
With paraformaldehyde; In hydrogenchloride; ethanol; isopropyl alcohol; EXAMPLE 1 4'-Propyl-2-methyl-3-pyrrolidinopropiophenone To a solution of 5.00 g of 4'-Propylpropiophenone in 10 ml of isopropanol were added 3.00 g of <strong>[25150-61-2]pyrrolidine hydrochloride</strong>, 1.30 g of paraformaldehyde and 0.5 ml of 40% ethanolic hydrogen chloride, and the mixture was refluxed for 4.5 hours and evaporated. The residue was dissolved in aqueous hydrochloric acid and washed with ether. The aqueous layer was made alkaline with potassium carbonate and extracted with ether. The extract was washed with water, dried and evaporated. The residue was dissolved in ether and acidified with 40% ethanolic hydrogen chloride. The precipitate was filtered, washed with a mixture of ethanol and ether, and recrystallized from methyl ethyl ketone to give 1.50 g of hydrochloride of the desired compound as colorless needles, mp 151-152. Analysis for C17 H25 NO.HCl: Calculated %: C, 69.02; H, 8.86; N, 4.73; Found %: C, 68.75; H, 9.23; N, 4.64
 

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