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Chemical Structure| 56440-28-9 Chemical Structure| 56440-28-9

Structure of 56440-28-9

Chemical Structure| 56440-28-9

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Product Details of [ 56440-28-9 ]

CAS No. :56440-28-9
Formula : C4H9ClN2O
M.W : 136.58
SMILES Code : O=C1NCC[C@@H]1N.[H]Cl
MDL No. :MFCD08273939
InChI Key :QRKDBIIHVIKHJQ-DFWYDOINSA-N
Pubchem ID :53302067

Safety of [ 56440-28-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of [ 56440-28-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 56440-28-9 ]

[ 56440-28-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 56440-28-9 ]
  • [ 79286-79-6 ]
YieldReaction ConditionsOperation in experiment
In diethyl ether; REFERENCE EXAMPLE 2 Preparation of (3S)-3-aminopyrrolidine: (3S)-3-Amino-2-pyrrolidone hydrochloride (1.5 g) [cf. Beilsteins Handbuch der Organischen Chemie, Drittes und Viertes Erganzungswerk, issued in 1980, page 6401] is suspended in diethyl ether (50 ml), and to the suspension is added lithium aluminum hydride (1.0 g), and the mixture is refluxed with stirring for 48 hours. While stirring under ice cooling, a small amount of ice is added to the reaction mixture to decompose excess lithium aluminum hydride, and the insoluble materials are removed by filtration. The filtrate is dried over anhydrus sodium sulfate, and distilled under reduced pressure to remove diethyl ether. The residue is distilled and fractions of 30-100 C./25 mmHg are collected to give crude (3S)-3-aminopyrrolidine (216 mg) as an oily substance. [alpha]D20 -6.9 (c=1, H2 O) The above crude (3R)-3-aminopyrrolidine is purified in the form of L(+)-tartrate as follows.
 

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