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Type HazMat fee for 500 gram (Estimated)
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Chemical Structure| 56875-55-9 Chemical Structure| 56875-55-9

Structure of 56875-55-9

Chemical Structure| 56875-55-9

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Product Details of [ 56875-55-9 ]

CAS No. :56875-55-9
Formula : C11H9ClO3S
M.W : 256.71
SMILES Code : O=S(C1=C2C=CC=CC2=C(OC)C=C1)(Cl)=O
MDL No. :MFCD08752807

Safety of [ 56875-55-9 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314
Precautionary Statements:P264-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P403+P233-P501
Class:8
UN#:3261
Packing Group:

Application In Synthesis of [ 56875-55-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 56875-55-9 ]

[ 56875-55-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 56875-55-9 ]
  • [ 369-26-6 ]
  • C19H16FNO5S [ No CAS ]
YieldReaction ConditionsOperation in experiment
With pyridine; In dichloromethane; at 0 - 20℃; for 8h;Cooling with ice; General procedure: To a solution of compound 11a (154 mg, 1.0 mmol) in anhydrous CH2Cl2 (10 mL) was added 3,5-dichlorobenzoyl chloride (209 mg, 1.0 mmol) and pyridine (241 mL 3.0 mmol) under ice bath. After stirring at room temperature for about 8 h, the solvent was removed in vacuum. The resulting residue was dissolved in NaOH (1 M) water solution (3 mL) and CH3OH (3 mL) and stirred for another 2 h. Then the solvent was removed under vacuum, and the residue was acidied to pH 2 or below with HCl (1 M) water solution. The solution was extracted with ethyl acetate twice and the combined organics were dried over anhydrous sodium sulfate and concentrated in vacuum. The resulting residue was puried by silica gel chromatography to give the desired compound as a white solid (234 mg, yield 85.0percent)
  • 2
  • [ 56875-55-9 ]
  • [ 84832-02-0 ]
  • C19H15F2NO5S [ No CAS ]
YieldReaction ConditionsOperation in experiment
With pyridine; In dichloromethane; at 0 - 20℃; for 8h;Cooling with ice; General procedure: To a solution of compound 11a (154 mg, 1.0 mmol) in anhydrous CH2Cl2 (10 mL) was added 3,5-dichlorobenzoyl chloride (209 mg, 1.0 mmol) and pyridine (241 mL 3.0 mmol) under ice bath. After stirring at room temperature for about 8 h, the solvent was removed in vacuum. The resulting residue was dissolved in NaOH (1 M) water solution (3 mL) and CH3OH (3 mL) and stirred for another 2 h. Then the solvent was removed under vacuum, and the residue was acidied to pH 2 or below with HCl (1 M) water solution. The solution was extracted with ethyl acetate twice and the combined organics were dried over anhydrous sodium sulfate and concentrated in vacuum. The resulting residue was puried by silica gel chromatography to give the desired compound as a white solid (234 mg, yield 85.0%)
 

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