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Chemical Structure| 56879-47-1 Chemical Structure| 56879-47-1

Structure of 56879-47-1

Chemical Structure| 56879-47-1

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Product Details of [ 56879-47-1 ]

CAS No. :56879-47-1
Formula : C6H11NO3
M.W : 145.16
SMILES Code : O=C(C1NCCCC1O)O
MDL No. :MFCD19217418

Safety of [ 56879-47-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

Application In Synthesis of [ 56879-47-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 56879-47-1 ]

[ 56879-47-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 68176-57-8 ]
  • [ 56879-47-1 ]
  • [ 1449473-59-9 ]
YieldReaction ConditionsOperation in experiment
General procedure: Example 75 2-(5- e/t-Butyl-1 H-benzimidazol-2-yl)piperidin-3-ol A 0.2M solution of 3-hydroxypiperidine-2-carboxylic acid (500 muIota_, 100 pmol) in DMA was added to a 0.2M solution of 4-terf-butyl-1 ,2-diaminobenzene (500 muIota_, 100 pmol) in DMA followed by BOP (44 mg, 100 pmol). The reaction was stirred at room temperature for 16 hours before concentrating in vacuo. A solvent mixture of THF/AcOH (5/1 , 1 mL) was added to the residue, and the reaction heated to 60°C for 16 hours. The reaction was cooled, concentrated in vacuo, dissolved in DMSO (1 mL) and purified using preparative HPLC (XTERRA-C18 (250 x 19 mm, 10 mu, mobile phase A: Acetonitrile, mobile phase B: 10mM ammonium acetate in water; eluting with a gradient of 10-70percent organic with a flow rate of 16 mL/min over 18 minutes) to afford the title compound. LCMS Rt =1 .33 minutes MS m/z 274 [M+H]+
 

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