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Chemical Structure| 57369-97-8 Chemical Structure| 57369-97-8

Structure of 57369-97-8

Chemical Structure| 57369-97-8

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Product Details of [ 57369-97-8 ]

CAS No. :57369-97-8
Formula : C8H5N3
M.W : 143.15
SMILES Code : N#CC1=CC(N)=CC(C#N)=C1
MDL No. :MFCD19203535
InChI Key :UBFORUHJOUPFHX-UHFFFAOYSA-N
Pubchem ID :19777619

Safety of [ 57369-97-8 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H331
Precautionary Statements:P261-P280-P301+P310-P311
Class:6.1
UN#:2811
Packing Group:

Application In Synthesis of [ 57369-97-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 57369-97-8 ]

[ 57369-97-8 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 23218-93-1 ]
  • [ 57369-97-8 ]
  • 2
  • [ 99066-80-5 ]
  • [ 57369-97-8 ]
  • 3
  • [ 57774-35-3 ]
  • [ 57369-97-8 ]
  • C34H19N5 [ No CAS ]
YieldReaction ConditionsOperation in experiment
31.1% With tri-tert-butyl phosphine; Cs2CO3; Palladium(0) bis(dibenzylideneacetone); In 5,5-dimethyl-1,3-cyclohexadiene; for 4h;Reflux; 1.5 g (10.5 mmol) of the intermediate (6) in a one-necked 250 mL flask,4'-bromo-[1.1'-biphenyl]-4-carbonitrile (4'-bromo-[1.1'-biphenyl]-4-carbonitrile) 6.0 g (23.1 mmol), CsCO310.2 g (31.4 mmol) and 150 mL of xylene were added together, and while stirring, 20.4 g (0.6 mmol) of Pd(dba),30.2 mL (0.8 mmol) of P(t-Bu) was added, and the mixture was heated under reflux and stirred for 4 hours.When the reaction is complete, the reaction is cooled to room temperature, the solvent is removed, methanol is added, stirred for 30 minutes, filtered to obtain a solid, acetone is added, stirred for 30 minutes, filtered to obtain a solid, dissolved with hot acetone, and passed through a pad covered with celite. was removed, added acetone, stirred for 3 to 4 hours, filtered to obtain a solid, and this was repeated twice to obtain 1.6 g (yield: 31.1%) of compound 2-74 (LT20-30-255) as a pale yellow-green solid.
 

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