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Type HazMat fee for 500 gram (Estimated)
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Chemical Structure| 57734-44-8 Chemical Structure| 57734-44-8

Structure of 57734-44-8

Chemical Structure| 57734-44-8

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Product Details of [ 57734-44-8 ]

CAS No. :57734-44-8
Formula : C12H18N2
M.W : 190.29
SMILES Code : NCC1N(CC2=CC=CC=C2)CCC1
MDL No. :MFCD10003507

Safety of [ 57734-44-8 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314
Precautionary Statements:P264-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P403+P233-P501
Class:8
UN#:2735
Packing Group:

Application In Synthesis of [ 57734-44-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 57734-44-8 ]

[ 57734-44-8 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 57734-44-8 ]
  • [ 72411-89-3 ]
  • C18H22N4O2*2ClH*H2O [ No CAS ]
  • 2
  • [ 38871-41-9 ]
  • [ 57734-44-8 ]
  • N-(1'benzyl-2-pyrrolidylmethyl)-1,4-benzodioxane-5-carboxamide phosphate [ No CAS ]
YieldReaction ConditionsOperation in experiment
61% With phosphoric acid; ammonia; In ethanol; chloroform; EXAMPLE 6 N-(1'benzyl-2-pyrrolidylmethyl)-1,4-benzodioxane-5-carboxamide phosphate 440 ml of chloroform and 110 g of 1-benzyl-2-aminomethylpyrrolidine were introduced into a balloon flask provided with an agitator and a thermometer, and then, at a temperature of from 5-10 C., 110 g of <strong>[38871-41-9]1,4-benzodioxane-5-carbonyl chloride</strong> was added. After agitation of the mixture and addition of 3 liters of water, chloroform was removed. The solution was treated with ammonia and then the precipitate was extracted with methylene chloride. The organic solution was dried and then the solvent was removed. The resulting compound dissolved in absolute ethanol was treated with 30 ml of 85% phosphoric acid. The precipitate formed was dried off, washed with ethanol and dried. 153 g of N-(1-benzyl-2-pyrrolidylmethyl)-1,4-benzodioxane-5-carboxamide phosphate was produced (M.P.: 165 C.; yield: 61%).
 

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