Home Cart Sign in  
Chemical Structure| 578709-06-5 Chemical Structure| 578709-06-5

Structure of 578709-06-5

Chemical Structure| 578709-06-5

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 578709-06-5 ]

CAS No. :578709-06-5
Formula : C12H14ClN3
M.W : 235.71
SMILES Code : ClC1=CC=C2C(NC(C3CCNCC3)=N2)=C1
MDL No. :MFCD09027608

Safety of [ 578709-06-5 ]

Application In Synthesis of [ 578709-06-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 578709-06-5 ]

[ 578709-06-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 22123-14-4 ]
  • [ 578709-06-5 ]
  • 6-chloro-2-(1-(6-methyl-4-pyridin-2-yl)piperidin-4-yl)-1H-benzo[d]imidazole [ No CAS ]
YieldReaction ConditionsOperation in experiment
62% With sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 120 - 125℃; for 18h;Inert atmosphere; General procedure: A mixture of 2-chloro-6-phenyl/methyl-4-(trifluoromethyl)pyridine 3 (1 mmol) and 6-substituted-2-(piperidin-4-yl)-1H-benzo[d] imidazole (1.2 mmol) was charged and added NaHCO3 (3.8 mmol), and DMF (5 mL) were added.The reaction mixture was heated for 18 h at 120-125 C in N2 atmosphere. Progress of the reaction was monitored byTLC. The reaction mixture was cooled and poured onto crushed ice. That obtained solid was filtered, washed with water, hot 4N HCl and followed by water. The obtained crude product was purified at the column chromatography over silica gel using the solvent system 4:6 ethyl acetate:hexane as eluent to give the title compounds (4a-h).
 

Historical Records

Technical Information

Categories