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Chemical Structure| 585517-66-4 Chemical Structure| 585517-66-4

Structure of 585517-66-4

Chemical Structure| 585517-66-4

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Product Details of [ 585517-66-4 ]

CAS No. :585517-66-4
Formula : C14H14N2O
M.W : 226.27
SMILES Code : O=C(NC1=CC=CC(N)=C1)C2=CC=CC(C)=C2
MDL No. :MFCD01806272

Safety of [ 585517-66-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

Application In Synthesis of [ 585517-66-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 585517-66-4 ]

[ 585517-66-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 42926-52-3 ]
  • [ 585517-66-4 ]
  • [ 1622869-16-2 ]
YieldReaction ConditionsOperation in experiment
With triethylamine; In acetonitrile; at 80℃; for 5h; General procedure: To a vial containing acetonitrile (10mL) was added N-(3-aminophenyl)-3-methylbenzamide (0.30g, 1.32mmol), NEt3 (0.28mL, 1.98mmol) and 2-methoxybenzoyl chloride (0.22mL, 1.45mmol), and the resulting solution was capped and heated at 80C for 5h. After cooling to room temperature, the solution was concentrated, and the residue was dissolved in CH2Cl2 (10mL). The organic extract was washed with saturated aqueous NaHCO3 (2×8mL), separated, and dried (MgSO4). Filtration and concentration generated a residue that was purified by reverse-phase MPLC (10-100% acetonitrile/water) to afford 2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide (0.16g, 0.43mmol, 33% yield).
 

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