[ CAS No. 58677-05-7 ] {[proInfo.proName]}

Name: 58677-05-7|Ethyl 2-amino-5-methylbenzoate|95%
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Quality Control of [ 58677-05-7 ]

COA NMR CNMR HPLC LC-MS

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SDS Specification

Alternatived Products of [ 58677-05-7 ]

Product Details of [ 58677-05-7 ]

CAS No. :	58677-05-7	MDL No. :	MFCD00115547
Formula :	C₁₀H₁₃NO₂	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	OROMVXLWBWNXIW-UHFFFAOYSA-N
M.W :	179.22	Pubchem ID :	12327280
Synonyms :

Calculated chemistry of [ 58677-05-7 ]

Physicochemical Properties

Num. heavy atoms :	13
Num. arom. heavy atoms :	6
Fraction Csp3 :	0.3
Num. rotatable bonds :	3
Num. H-bond acceptors :	2.0
Num. H-bond donors :	1.0
Molar Refractivity :	51.9
TPSA :	52.32 Å²

Pharmacokinetics

GI absorption :	High
BBB permeant :	Yes
P-gp substrate :	No
CYP1A2 inhibitor :	Yes
CYP2C19 inhibitor :	No
CYP2C9 inhibitor :	No
CYP2D6 inhibitor :	No
CYP3A4 inhibitor :	No
Log Kp (skin permeation) :	-5.31 cm/s

Lipophilicity

Log Po/w (iLOGP) :	2.14
Log Po/w (XLOGP3) :	2.93
Log Po/w (WLOGP) :	1.76
Log Po/w (MLOGP) :	1.94
Log Po/w (SILICOS-IT) :	1.8
Consensus Log Po/w :	2.11

Druglikeness

Lipinski :	0.0
Ghose :	None
Veber :	0.0
Egan :	0.0
Muegge :	1.0
Bioavailability Score :	0.55

Water Solubility

Log S (ESOL) :	-2.94
Solubility :	0.205 mg/ml ; 0.00115 mol/l
Class :	Soluble
Log S (Ali) :	-3.69
Solubility :	0.0366 mg/ml ; 0.000204 mol/l
Class :	Soluble
Log S (SILICOS-IT) :	-2.9
Solubility :	0.223 mg/ml ; 0.00124 mol/l
Class :	Soluble

Medicinal Chemistry

PAINS :	0.0 alert
Brenk :	1.0 alert
Leadlikeness :	1.0
Synthetic accessibility :	1.58

Safety of [ 58677-05-7 ]

Signal Word:	Warning	Class:	N/A
Precautionary Statements:	P261-P305+P351+P338	UN#:	N/A
Hazard Statements:	H302-H315-H319-H335	Packing Group:	N/A
GHS Pictogram:

Application In Synthesis of [ 58677-05-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Upstream synthesis route of [ 58677-05-7 ]
Downstream synthetic route of [ 58677-05-7 ]

[ 58677-05-7 ] Synthesis Path-Upstream 1~3

1
[ 54064-40-3 ]
[ 58677-05-7 ]

Reference： [1] European Journal of Organic Chemistry, 2010, # 24, p. 4662 - 4670
[2] European Journal of Medicinal Chemistry, 2016, vol. 121, p. 747 - 757

2
[ 2941-78-8 ]
[ 58677-05-7 ]

Yield	Reaction Conditions	Operation in experiment
80%	With hydrogenchloride In ethanol	a 2-Amino-5-methyl-benzoic Acid Ethyl Ester (Compound of Formula VII) As in scheme 1 step 1 (according to S. P. Acharya and J. B. Hynes, J. Heterocyclic Chem., 1975, 12, 1283) from 2-amino-5-methylbenzoic acid, ethanol and HCl gas to afford the product. Yield: 80percent. White solid, m/z (ISP) 178 (M-H)

Reference： [1] Patent: US2003/55042, 2003, A1,

3
[ 2941-78-8 ]
[ 64-17-5 ]
[ 58677-05-7 ]

Reference： [1] ACS Medicinal Chemistry Letters, 2015, vol. 6, # 3, p. 308 - 312
[2] Journal of Chemical Research, Miniprint, 1986, # 7, p. 2001 - 2025
[3] Journal of Organic Chemistry, 2018, vol. 83, # 3, p. 1154 - 1159

[ 58677-05-7 ] Synthesis Path-Downstream 1~37

1
[ 58677-05-7 ]
[ 29671-92-9 ]
[ 50440-82-9 ]

Reference： [1]Journal of Medicinal Chemistry,1990,vol. 33,p. 2045 - 2051

2
[ 2941-78-8 ]
[ 64-17-5 ]
[ 58677-05-7 ]

Reference： [1]ACS Medicinal Chemistry Letters,2015,vol. 6,p. 308 - 312
[2]Journal of Chemical Research, Miniprint,1986,p. 2001 - 2025
[3]Journal of Organic Chemistry,2018,vol. 83,p. 1154 - 1159

3
[ 463-71-8 ]
[ 58677-05-7 ]
[ 106012-79-7 ]

Reference： [1]Journal of Chemical Research, Miniprint,1986,p. 2001 - 2025

4
[ 58677-05-7 ]
[ 333-20-0 ]
[ 83494-90-0 ]

Reference： [1]Journal of Chemical Research, Miniprint,1986,p. 2001 - 2025

7
[ 58677-05-7 ]
[ 543740-77-8 ]

Reference： [1]Tetrahedron,2003,vol. 59,p. 1571 - 1587

8
[ 58677-05-7 ]
[ 320740-16-7 ]

Reference： [1]Tetrahedron,2003,vol. 59,p. 1571 - 1587

9
[ 58677-05-7 ]
2-butyl-5-methyl-1H-indole-7-carboxamide [ No CAS ]

Reference： [1]Tetrahedron,2003,vol. 59,p. 1571 - 1587

10
[ 58677-05-7 ]
5-methyl-2-phenyl-1H-indole-7-carboxamide [ No CAS ]

Reference： [1]Tetrahedron,2003,vol. 59,p. 1571 - 1587

11
[ 58677-05-7 ]
2-amino-3-iodo-5-methyl-benzamide; compound with trifluoro-acetic acid [ No CAS ]

Reference： [1]Tetrahedron,2003,vol. 59,p. 1571 - 1587

12
[ 58677-05-7 ]
2-amino-3-hex-1-ynyl-5-methyl-benzamide; compound with trifluoro-acetic acid [ No CAS ]

Reference： [1]Tetrahedron,2003,vol. 59,p. 1571 - 1587

13
[ 58677-05-7 ]
2-amino-5-methyl-3-phenylethynyl-benzamide; compound with trifluoro-acetic acid [ No CAS ]

Reference： [1]Tetrahedron,2003,vol. 59,p. 1571 - 1587

14
[ 58677-05-7 ]
[ 62483-65-2 ]

Reference： [1]Journal of Chemical Research, Miniprint,1986,p. 2001 - 2025
[2]Journal of Chemical Research, Miniprint,1986,p. 2001 - 2025

15
[ 58677-05-7 ]
[ 49681-94-9 ]

Reference： [1]Journal of Chemical Research, Miniprint,1986,p. 2001 - 2025

16
[ 58677-05-7 ]
[ 80195-32-0 ]

Reference： [1]Journal of Chemical Research, Miniprint,1986,p. 2001 - 2025

17
[ 58677-05-7 ]
3-amino-6-methyl-2-methylthioquinazolin-4(3H)-one [ No CAS ]

Reference： [1]Journal of Chemical Research, Miniprint,1986,p. 2001 - 2025

18
[ 58677-05-7 ]
[ 106012-87-7 ]

Reference： [1]Journal of Chemical Research, Miniprint,1986,p. 2001 - 2025

19
[ 58677-05-7 ]
[ 80195-28-4 ]

Reference： [1]Journal of Chemical Research, Miniprint,1986,p. 2001 - 2025

20
[ 2941-78-8 ]
[ 58677-05-7 ]

Yield	Reaction Conditions	Operation in experiment
80%	With hydrogenchloride; In ethanol;	a 2-Amino-5-methyl-benzoic Acid Ethyl Ester (Compound of Formula VII) As in scheme 1 step 1 (according to S. P. Acharya and J. B. Hynes, J. Heterocyclic Chem., 1975, 12, 1283) from 2-amino-5-methylbenzoic acid, ethanol and HCl gas to afford the product. Yield: 80%. White solid, m/z (ISP) 178 (M-H)

Reference： [1]Patent: US2003/55042,2003,A1

21
[ 58677-05-7 ]
[ 77-78-1 ]
5-methyl-2-methylaminobenzyl alcohol [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
		a) 5-Methyl-2-methylaminobenzyl chloride hydrochloride <strong>[58677-05-7]Ethyl 2-amino-5-methylbenzoate</strong> was treated with dimethylsulfuric acid to give a N-methylated product. The N-methylated product was reduced using lithium aluminum hydride to give 5-methyl-2-methylaminobenzyl alcohol.

Reference： [1]Patent: US5082943,1992,A

22
[ 1119089-35-8 ]
[ 58677-05-7 ]
[ 1119086-11-1 ]

Yield	Reaction Conditions	Operation in experiment
65%		Example 51; <n="104"/>2-(6-(3-Methoxyphenyl)-5-methylpyridin-3-ylamino)-5-methylbenzoic acidIn a schlenck tube, a mixture of Intermediate 33 (2.55 mmol, 0.71 g), Intermediate 55 (2.57 mmol, 0.46 g), BINAP (0.25 mmol, 0.158 g), Pd2(dba)3 (0.13 mmol, 0.116 g) and NaO1Bu (6.35 mmol, 0.610 g) in toluene (20 ml) was heated at 11O0C for 12 hours, under argon atmosphere. The solvent was evaporated, the solid residue was suspended in water, the pH was taken to 6.5 and extracted with CHCI3. The crude mixture was purified by flash chromatography over SiO2 eluting with mixtures of hexane/ethyl acetate affording 0.580 g (yield 65%) of the expected compound. delta 1H NMR (300 MHz, CDCI3): 2.28 (s, 3H)1 2.34 (s, 3H), 3.85 (s, 3H), 6.95 (d, 1 H), 7.08(s, 2H), 7.23 (d, 1 H), 7.36 (t, 1H), 7.58 (s, 1 H), 7.83 (s, 1 H), 8.51 (s, 1 H).ESI/MS (m/e, %): 349 [(M+1) 100].

Reference： [1]Patent: WO2009/21696,2009,A1 .Location in patent: Page/Page column 102-103

23
[ 50-00-0 ]
[ 58677-05-7 ]
diethyl 2,8-dimethyl-6H,12H-5,11-methanodibenzo[b,f][1,5]diazocine-4,10-dicarboxylate [ No CAS ]

Reference： [1]European Journal of Organic Chemistry,2010,p. 4662 - 4670

24
[ 54064-40-3 ]
[ 58677-05-7 ]

Yield	Reaction Conditions	Operation in experiment
	With 10% palladium hydroxide on charcoal; hydrogen; In methanol; at 20℃; under 760.051 Torr; for 12h;	General procedure: A solution ofethyl 2-nitrobenzoate (917 mg, 4.7 mmol) in MeOH (20 mL) and CH3COOH(0.1 mL) was subjected to two cycles N2/vacuum. Pd(OH)2/C10% wt (66 mg, 0.01 eq.) was added and the reaction mixture stirred at roomtemperature under H2 (1 atm) for 12 h. Propanal (337 muL, 4.7 mmol)and Pd(OH)2/C 10% wt (66 mg, 0.01 eq.) were added, and the reactionstirred at room temperature under H2 (1 atm) for additional 12 h.The suspension was filtered through Celite washing twice with CH2Cl2(20 mL). The solution recovered was evaporated under reduced pressure giving anoil after purification by flash chromatography (PE/AcOEt: 4/1). The oil obtained(1 eq.) was dissolved in dry CH2Cl2, and ethyl malonyl chloride(1 eq.) was added. The reaction mixture was stirred at room temperature under N2overnight. The reaction mixture was diluted with CH2Cl2and washed with a saturated solution of NaHCO3. Organic layers werethen washed with brine, dried over dry Na2SO4, filteredand evaporated under reduced pressure giving the expected compound after flashchromatography purification.

Reference： [1]European Journal of Organic Chemistry,2010,p. 4662 - 4670
[2]European Journal of Medicinal Chemistry,2016,vol. 121,p. 747 - 757

25
[ 58677-05-7 ]
N-(4-chlorobenzyl)-4-((2-(dimethylamino)ethyl)amino)-6-methylquinazoline-2-carboxamide [ No CAS ]

Reference： [1]ACS Medicinal Chemistry Letters,2015,vol. 6,p. 308 - 312

26
[ 58677-05-7 ]
[ 620957-95-1 ]

Reference： [1]ACS Medicinal Chemistry Letters,2015,vol. 6,p. 308 - 312

27
[ 58677-05-7 ]
tert-butyl (2-((2-((4-chlorophenyl)carbamoyl)-6-methylquinazolin-4-yl)amino)ethyl)carbamate [ No CAS ]

Reference： [1]ACS Medicinal Chemistry Letters,2015,vol. 6,p. 308 - 312

28
[ 58677-05-7 ]
ethyl 4-((2-((tert-butoxycarbonyl)amino)ethyl)amino)-6-methylquinazoline-2-carboxylate [ No CAS ]

Reference： [1]ACS Medicinal Chemistry Letters,2015,vol. 6,p. 308 - 312

29
[ 58677-05-7 ]
C₁₈H₁₈ClN₅O*ClH [ No CAS ]

Reference： [1]ACS Medicinal Chemistry Letters,2015,vol. 6,p. 308 - 312

30
[ 58677-05-7 ]
ethyl 4-((2-(dimethylamino)ethyl)amino)-6-methylquinazoline-2-carboxylate [ No CAS ]

Reference： [1]ACS Medicinal Chemistry Letters,2015,vol. 6,p. 308 - 312

31
[ 58677-05-7 ]
[ 623-49-4 ]
[ 869294-64-4 ]

Reference： [1]ACS Medicinal Chemistry Letters,2015,vol. 6,p. 308 - 312

32
[ 58677-05-7 ]
C₂₄H₂₆N₂O₅ [ No CAS ]

Reference： [1]European Journal of Medicinal Chemistry,2016,vol. 121,p. 747 - 757

33
[ 58677-05-7 ]
ethyl-2-(3-ethoxy-3-oxo-N-propylpropanamido)-5-methylbenzoate [ No CAS ]

Reference： [1]European Journal of Medicinal Chemistry,2016,vol. 121,p. 747 - 757

34
[ 58677-05-7 ]
ethyl 1-propyl-1,2-dihydro-4-hydroxy-6-methyl-2-oxo-quinoline-3-carboxylate [ No CAS ]

Reference： [1]European Journal of Medicinal Chemistry,2016,vol. 121,p. 747 - 757

35
[ 58677-05-7 ]
[ 123-38-6 ]
C₁₃H₁₉NO₂ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With 10% palladium hydroxide on charcoal; hydrogen; In methanol; at 20℃; under 760.051 Torr;	General procedure: A solution ofethyl 2-nitrobenzoate (917 mg, 4.7 mmol) in MeOH (20 mL) and CH3COOH(0.1 mL) was subjected to two cycles N2/vacuum. Pd(OH)2/C10% wt (66 mg, 0.01 eq.) was added and the reaction mixture stirred at roomtemperature under H2 (1 atm) for 12 h. Propanal (337 muL, 4.7 mmol)and Pd(OH)2/C 10% wt (66 mg, 0.01 eq.) were added, and the reactionstirred at room temperature under H2 (1 atm) for additional 12 h.The suspension was filtered through Celite washing twice with CH2Cl2(20 mL). The solution recovered was evaporated under reduced pressure giving anoil after purification by flash chromatography (PE/AcOEt: 4/1). The oil obtained(1 eq.) was dissolved in dry CH2Cl2, and ethyl malonyl chloride(1 eq.) was added. The reaction mixture was stirred at room temperature under N2overnight. The reaction mixture was diluted with CH2Cl2and washed with a saturated solution of NaHCO3. Organic layers werethen washed with brine, dried over dry Na2SO4, filteredand evaporated under reduced pressure giving the expected compound after flashchromatography purification.

Reference： [1]European Journal of Medicinal Chemistry,2016,vol. 121,p. 747 - 757

36
[ 58677-05-7 ]
[ 693-13-0 ]
3-isopropyl-2-(isopropylamino)-6-methylquinazolin-4(3H)-one [ No CAS ]

Reference： [1]Journal of Organic Chemistry,2018,vol. 83,p. 1154 - 1159

37
[ 577-19-5 ]
[ 58677-05-7 ]
ethyl 5-methyl-2-((2-nitrophenyl)amino)benzoate [ No CAS ]

Reference： [1]Patent: WO2019/198692,2019,A1 .Location in patent: Paragraph 0438

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Ghs Precautionary Statements

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P101	If medical advice is needed,have product container or label at hand.
P102	Keep out of reach of children.
P103	Read label before use
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Code	Phrase
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P222	Do not allow contact with air.
P223	Keep away from any possible contact with water, because of violent reaction and possible flash fire.
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P233	Keep container tightly closed.
P234	Keep only in original container.
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P242	Use only non-sparking tools.
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P260	Do not breathe dust/fume/gas/mist/vapours/spray.
P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P262	Do not get in eyes, on skin, or on clothing.
P263	Avoid contact during pregnancy/while nursing.
P264	Wash hands thoroughly after handling.
P265	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P271	Use only outdoors or in a well-ventilated area.
P272	Contaminated work clothing should not be allowed out of the workplace.
P273	Avoid release to the environment.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P281	Use personal protective equipment as required.
P282	Wear cold insulating gloves/face shield/eye protection.
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P284	Wear respiratory protection.
P285	In case of inadequate ventilation wear respiratory protection.
P231 + P232	Handle under inert gas. Protect from moisture.
P235 + P410	Keep cool. Protect from sunlight.
Response
Code	Phrase
P301	IF SWALLOWED:
P304	IF INHALED:
P305	IF IN EYES:
P306	IF ON CLOTHING:
P307	IF exposed:
P308	IF exposed or concerned:
P309	IF exposed or if you feel unwell:
P310	Immediately call a POISON CENTER or doctor/physician.
P311	Call a POISON CENTER or doctor/physician.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P313	Get medical advice/attention.
P314	Get medical advice/attention if you feel unwell.
P315	Get immediate medical advice/attention.
P320
P302 + P352	IF ON SKIN: wash with plenty of soap and water.
P321
P322
P330	Rinse mouth.
P331	Do NOT induce vomiting.
P332	IF SKIN irritation occurs:
P333	If skin irritation or rash occurs:
P334	Immerse in cool water/wrap n wet bandages.
P335	Brush off loose particles from skin.
P336	Thaw frosted parts with lukewarm water. Do not rub affected area.
P337	If eye irritation persists:
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P340	Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P341	If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342	If experiencing respiratory symptoms:
P350	Gently wash with plenty of soap and water.
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P352	Wash with plenty of soap and water.
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P374	Fight fire with normal precautions from a reasonable distance.
P376	Stop leak if safe to do so. Oxidising gases (section 2.4) 1
P377	Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P378
P380	Evacuate area.
P381	Eliminate all ignition sources if safe to do so.
P390	Absorb spillage to prevent material damage.
P391	Collect spillage. Hazardous to the aquatic environment
P301 + P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301 + P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
P303 + P361 + P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
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P401
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P413
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P422
P402 + P404	Store in a dry place. Store in a closed container.
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Disposal
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Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
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Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 58677-05-7 ] {[proInfo.proName]}

Quality Control of [ 58677-05-7 ]

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[ 58677-05-7 ] Synthesis Path-Upstream 1~3

[ 58677-05-7 ] Synthesis Path-Downstream 1~37

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Aryls

Esters

Amines

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[ 58677-05-7 ]