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Chemical Structure| 59456-20-1 Chemical Structure| 59456-20-1

Structure of 59456-20-1

Chemical Structure| 59456-20-1

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Product Details of [ 59456-20-1 ]

CAS No. :59456-20-1
Formula : C10H13I
M.W : 260.11
SMILES Code : CC(I)CCC1=CC=CC=C1

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Application In Synthesis of [ 59456-20-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 59456-20-1 ]

[ 59456-20-1 ] Synthesis Path-Downstream   1~5

  • 2
  • [ 59456-20-1 ]
  • [Fe(bis(oxazolinylphenyl)amido-Ph)Ph] [ No CAS ]
  • [ 1520-44-1 ]
  • 3
  • [ 59456-20-1 ]
  • [ 100-59-4 ]
  • [ 1520-44-1 ]
YieldReaction ConditionsOperation in experiment
95% With [Fe(bis(oxazolinylphenyl)amido-Ph)Cl2]; In tetrahydrofuran; at -40℃; for 1.0h;Inert atmosphere; General procedure: Alkyl halide (Method A: 0.5 mmol, Method B: 0.25 mmol) was dissolved in THF [3.0 mL (A)/1.5 mL (B)] and a stock solution (25 mM) of [Fe(Bopa-tBu)Cl2] (1d) [1.0 mL (A)/0.5 mL (B)] was added. Afterwards PhMgCl (1.00 M) [0.5 mL (A)/0.25 mL (B)] was added over a time period of 15 min. The solution was stirred for another 45 min. Method A: The reaction was then quenched with H2O (20 mL), acidified with aq 1 M HCl, and extracted with CH2Cl2 (3 × 20 mL). The crude extract was dried (Na2SO4) and further purified by chromatography on silica gel (eluent: 1% to 45% EtOAc in hexanes). Method B: The reaction was quenched by adding EtOH (0.5 mL). The reaction mixture was transferred on a preparative TLC plate and then further separated (eluent:EtOAc-hexanes).
  • 4
  • [ 23418-91-9 ]
  • [ 59456-20-1 ]
  • [ 1520-44-1 ]
 

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