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Chemical Structure| 5950-39-0 Chemical Structure| 5950-39-0

Structure of 5950-39-0

Chemical Structure| 5950-39-0

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Product Details of [ 5950-39-0 ]

CAS No. :5950-39-0
Formula : C6H11NO2
M.W : 129.16
SMILES Code : O=C(C1NC1)OC(C)C
MDL No. :MFCD12913261

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Application In Synthesis of [ 5950-39-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 5950-39-0 ]

[ 5950-39-0 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 7635-54-3 ]
  • [ 5950-39-0 ]
  • 2-isopropyl 2-(-)-menthyl aziridine-2,2-dicarboxylate [ No CAS ]
  • 2
  • [ 7635-54-3 ]
  • [ 5950-39-0 ]
  • 1-(-)-menthyloxycarbonyl-aziridine-2-carboxylic acid isopropyl ester [ No CAS ]
YieldReaction ConditionsOperation in experiment
79% With N-ethyl-N,N-diisopropylamine; In acetone; at 0 - 20℃; General procedure: 1.0 equiv of aziridine-2-carboxylic acid ester was mixed withacetone (2 mL of acetone for 1 mmol of ester) and 2.5 equiv ofdiisopropylethylamine. The reaction mixturewas cooled to 0 C and1.0 equiv of alkyl chloroformate was added. The reaction mixturewas stirred at room temperature 3e5 h. Precipitate was filtered offand solvent was evaporated in vacuo, resulting oil was purified bycolumn chromatography on silica gel (200 mL for 1 g of mixture)with PEeEtOAc 4:1 as an eluent.
 

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