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Chemical Structure| 59882-98-3 Chemical Structure| 59882-98-3

Structure of 59882-98-3

Chemical Structure| 59882-98-3

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Product Details of [ 59882-98-3 ]

CAS No. :59882-98-3
Formula : C12H10Br2
M.W : 314.02
SMILES Code : BrCC1=CC=C2C=CC=CC2=C1CBr
MDL No. :MFCD00091071
Boiling Point : No data available

Safety of [ 59882-98-3 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314
Precautionary Statements:P264-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P403+P233-P501
Class:8
UN#:3261
Packing Group:

Application In Synthesis of [ 59882-98-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 59882-98-3 ]

[ 59882-98-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 59882-98-3 ]
  • [ 42303-42-4 ]
  • 2-(1'-Hydroxymethylcyclopropyl)benz[e]isoindoline hydrochloride [ No CAS ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; In tetrahydrofuran; chloroform; water; EXAMPLE 49 2-(1'-Hydroxymethylcyclopropyl)benz[e]isoindoline hydrochloride Ethyl <strong>[42303-42-4]1-aminocyclopropanecarboxylate hydrochloride</strong> (16 g) in chloroform (50 ml) was added to 1,2-bis(bromomethyl)naphthalene (40 g) and potassium carbonate (40 g) in chloroform (200 ml) kept at 60. The reaction mixture was refluxed for a further 6 hr and then filtered; the filtrate was evaporated to dryness and the residue [i.e. crude 2-(1'-carbethoxycyclopropyl)benz[e]isoindoline] was dissolved in THF (150 ml) and added to lithium aluminium hydride (10 g) in THF (100 ml) over 0.5 h. Water was then added and the resultant slurry was filtered and the filtrate was evaporated to dryness; the residue was partitioned between ether and water and the ether layer was extracted with concentrated hydrochloric acid. The acidic extract was evaporated to dryness to give a residue which was recrystallized from iso-propanol/ethyl acetate to give the title compound (5.9 g. m.p.192).
 

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