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Chemical Structure| 605-85-6 Chemical Structure| 605-85-6

Structure of 605-85-6

Chemical Structure| 605-85-6

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Product Details of [ 605-85-6 ]

CAS No. :605-85-6
Formula : C18H14O
M.W : 246.30
SMILES Code : O=C(C1=C2C=CC=CC2=CC=C1)CC3=CC=CC=C3
MDL No. :MFCD01109978

Safety of [ 605-85-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

Application In Synthesis of [ 605-85-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 605-85-6 ]

[ 605-85-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 178686-24-3 ]
  • [ 605-85-6 ]
  • [ 57-13-6 ]
  • [ 1283117-97-4 ]
YieldReaction ConditionsOperation in experiment
18.1% With hydrogenchloride; In ethanol; water; for 14.0h;Reflux; 00229] To a mixture of l-(naphthalen-l-yl)-2-phenylethanone (Intermediate 41) (250 mg, 1.02 mmol), <strong>[178686-24-3]3-ethoxy-4-hydroxy-5-nitrobenzaldehyde</strong> (257.3 mg, 1.22 mmol), and urea (182.9 mg, 3.05 mmol) in anhydrous EtOH (5mL) was added concentrated HCl solution (0.2 mL), and the reaction mixture was refluxed for 14 hours. The reaction mixture was concentrated under reduced pressure, and purified by column chromatography andpreparative HPLC to afford Compound 81 as a yellow solid (89 mg, yield: 18.1%). 1H NMR (DMSO- 6 400MHz): delta 10.30 (s, 1H), 8.84 (s, 1H), 6.49-7.89 (m, 8H), 6.87-7.23 (m, 7H), 5.26 (d, J = 2.8 Hz, 1H), 4.02-4.11 (m, 2H), 1.32- 1.36 (t, J = 6.8 Hz, 3H); MS (ESI): m/z 482.1 [M+l]+.
 

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