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Chemical Structure| 61062-55-3 Chemical Structure| 61062-55-3

Structure of 61062-55-3

Chemical Structure| 61062-55-3

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Product Details of [ 61062-55-3 ]

CAS No. :61062-55-3
Formula : C15H11F3O
M.W : 264.24
SMILES Code : FC(C1=CC=C(C(CC2=CC=CC=C2)=O)C=C1)(F)F
MDL No. :MFCD02260678

Safety of [ 61062-55-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 61062-55-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 61062-55-3 ]

[ 61062-55-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 178686-24-3 ]
  • [ 61062-55-3 ]
  • [ 57-13-6 ]
  • [ 1283118-42-2 ]
YieldReaction ConditionsOperation in experiment
39% With hydrogenchloride; In ethanol; water;Reflux; [00266] A mixture of 2-phenyl-l-(4-(trifluoromethyl)phenyl)ethanone (commercially available) (200 mg, 0.76 mmol), <strong>[178686-24-3]3-ethoxy-4-hydroxy-5-nitrobenzaldehyde</strong> (145 mg, 0.69 mmol), urea (124 mg, 2.06 mmol), cone. HC1 (0.06 mL, 0.69 mmol) in EtOH (5 mL) was refluxed overnight. Followed a standard aqueous/EtOAc workup, then purified by preparative HPLC to give Compound 113 (135.34 mg, yield 39%). 1H NMR (DMSO- 6 400 MHz): delta 8.83 (d, J = 1.6 Hz, 1H), 7.60-7.56 (m, 3H), 7.40-7.39 (m, 3H), 7.13 (s, 1H), 7.06-7.00 (m, 3H), 6.83-6.80 (m, 2H), 5.23 (d, J = 2.4 Hz, 1H), 4.06-3.97 (m, 2H), 1.30 (t, J = 7.2 Hz, 3H); MS (ESI): m/z 500.0 [M+l]+.
 

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