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Chemical Structure| 6127-15-7 Chemical Structure| 6127-15-7

Structure of 6127-15-7

Chemical Structure| 6127-15-7

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Product Details of [ 6127-15-7 ]

CAS No. :6127-15-7
Formula : C9H8BrNO3
M.W : 258.07
SMILES Code : CC(CC1=CC=C(Br)C=C1[N+]([O-])=O)=O
MDL No. :MFCD16660263
InChI Key :FIUOHGYINUTMQZ-UHFFFAOYSA-N
Pubchem ID :21814564

Safety of [ 6127-15-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362

Application In Synthesis of [ 6127-15-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 6127-15-7 ]

[ 6127-15-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 6127-15-7 ]
  • [ 6127-19-1 ]
YieldReaction ConditionsOperation in experiment
93% With carbon monoxide;cyclopentadienyl iron(II) dicarbonyl dimer; In toluene; at 120℃; for 5h; EXAMPLE 11 Synthesis of 6-bromo-2-methylindole In a stainless steel autoclave having an internal volume of 100 mL, 1.31 g (5.1 mmol) of 4-bromo-2-nitrophenylacetone, 72 mg (4 mol %) of cyclopentadienyidicarbonyliron (dimer) and 40 g of toluene were placed under nitrogen atmosphere. After the atmosphere inside of the reactor was substituted by nitrogen gas (10 kgf/cm2) three times, carbon monoxide gas was injected (30 kgf/cm2), and the resulting mixture was reacted at a temperature of 120 C. for 5 hours. After cooling, the reaction solution was subjected to quantitative analysis with liquid chromatography. As a result of it, it was confirmed that 5-fluoro-2-nitrophenylacetone was completely disappeared. The isolation treatment as mentioned above provided 1.00 g (yield 93.0%) of 6-bromo-2-methylindole.
 

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Technical Information

• Alkyl Halide Occurrence • Baeyer-Villiger Oxidation • Barbier Coupling Reaction • Baylis-Hillman Reaction • Benzylic Oxidation • Birch Reduction • Blanc Chloromethylation • Bucherer-Bergs Reaction • Clemmensen Reduction • Corey-Bakshi-Shibata (CBS) Reduction • Corey-Chaykovsky Reaction • Fischer Indole Synthesis • Friedel-Crafts Reaction • General Reactivity • Grignard Reaction • Henry Nitroaldol Reaction • Hiyama Cross-Coupling Reaction • Horner-Wadsworth-Emmons Reaction • Hydride Reductions • Hydrogenolysis of Benzyl Ether • Kinetics of Alkyl Halides • Kumada Cross-Coupling Reaction • Lawesson's Reagent • Leuckart-Wallach Reaction • McMurry Coupling • Meerwein-Ponndorf-Verley Reduction • Passerini Reaction • Paternò-Büchi Reaction • Petasis Reaction • Peterson Olefination • Pictet-Spengler Tetrahydroisoquinoline Synthesis • Preparation of Aldehydes and Ketones • Preparation of Alkylbenzene • Preparation of Amines • Prins Reaction • Reactions of Aldehydes and Ketones • Reactions of Alkyl Halides with Reducing Metals • Reactions of Amines • Reactions of Benzene and Substituted Benzenes • Reactions of Dihalides • Reformatsky Reaction • Robinson Annulation • Schlosser Modification of the Wittig Reaction • Schmidt Reaction • Specialized Acylation Reagents-Ketenes • Stille Coupling • Stobbe Condensation • Substitution and Elimination Reactions of Alkyl Halides • Suzuki Coupling • Tebbe Olefination • Ugi Reaction • Vilsmeier-Haack Reaction • Wittig Reaction • Wolff-Kishner Reduction

Categories

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[ 6127-15-7 ]

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