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Chemical Structure| 61338-35-0 Chemical Structure| 61338-35-0

Structure of 61338-35-0

Chemical Structure| 61338-35-0

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Product Details of [ 61338-35-0 ]

CAS No. :61338-35-0
Formula : C12H10N2O3
M.W : 230.22
SMILES Code : N#CC1=C(O)C2=C(OC)C=CC(OC)=C2N=C1

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Application In Synthesis of [ 61338-35-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 61338-35-0 ]

[ 61338-35-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 3575-32-4 ]
  • [ 61338-35-0 ]
  • 4-(3-dimethylamino-phenylamino)-5,8-dimethoxy-quinoline-3-carbonitrile [ No CAS ]
YieldReaction ConditionsOperation in experiment
With pyridine; In 2-ethoxy-ethanol; for 0.5h;Heating / reflux; A mixture of 0.148 g of 4-chloro-5,8-dimethoxy-3-quinolinecarbonitrile, 0.146 g of <strong>[3575-32-4]N,N-dimethyl-1,3-phenylenediamine dihydrochloride</strong>, 0.2 ml of pyridine, and 5 ml of ethoxyethanol was stirred under nitrogen, at reflux temperature for 30 minutes. Then the mixture was partitioned between ethyl acetate and saturated sodium chloride solution. The organic layer was dried and concentrated in vacuo. The residue thus obtained was chromatographed on silica gel eluting with ethyl acetate. Solvent was removed from product fractions giving 0.160 g of 4-(3-dimethylamino-phenylamino)-5,8-dimethoxy-quinoline-3-carbonitrile as a solid, mp 103-105C; mass spectrum (EI, m/e): M 348.1588.
 

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