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Chemical Structure| 62043-83-8 Chemical Structure| 62043-83-8

Structure of 62043-83-8

Chemical Structure| 62043-83-8

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Product Details of [ 62043-83-8 ]

CAS No. :62043-83-8
Formula : C15H11NO
M.W : 221.25
SMILES Code : O=C(C1=CC=CC=C1)CC2=CC=CC(C#N)=C2
MDL No. :MFCD02260691

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Application In Synthesis of [ 62043-83-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 62043-83-8 ]

[ 62043-83-8 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 178686-24-3 ]
  • [ 62043-83-8 ]
  • [ 57-13-6 ]
  • [ 1283117-38-3 ]
YieldReaction ConditionsOperation in experiment
2.5% With hydrogenchloride; In ethanol; water; for 48.0h;Reflux; [00174] To a solution of 3-(2-oxo-2-phenylethyl)benzonitrile (Intermediate 11) (80 mg, 0.36 mmol), <strong>[178686-24-3]3-ethoxy-4-hydroxy-5-nitrobenzaldehyde</strong> (76 mg, 0.36 mmol), and urea (50 mg, 1.08 mmol) in 20 mL of ethanol was added 0.2 mL of concentrated HCl solution, and the mixture was stirred at reflux for 2 days. After the solvent was removed under reduced pressure, the residue was purified by thin layer chromatography (PE:EtOAc=l :2) to give Compound 29 (22 mg, yield 2.5%). 1H NMR (CD3OD 400 MHz): delta 7.45 (s, 1H), 7.27 (d, J = 7.2 Hz, 1H), 7.21-7.18 (m, 5H), 7.12-7.05 (m, 3H), 6.98 (s, 1H), 5.20 (s, 1H), 3.97-3.94 (m, 2H), 1.30 (t, J = 6.8 Hz, 3H); MS (ESI): mJz 457..2 [M+l]+.
  • 2
  • [ 178686-24-3 ]
  • [ 62043-83-8 ]
  • [ 1283117-61-2 ]
 

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