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Chemical Structure| 622-29-7 Chemical Structure| 622-29-7

Structure of 622-29-7

Chemical Structure| 622-29-7

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Product Details of [ 622-29-7 ]

CAS No. :622-29-7
Formula : C8H9N
M.W : 119.16
SMILES Code : CN=CC1=CC=CC=C1
MDL No. :MFCD00008294
InChI Key :HXTGGPKOEKKUQO-UHFFFAOYSA-N
Pubchem ID :73954

Safety of [ 622-29-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340+P312-P305+P351+P338-P332+P313-P337+P313-P403+P233-P405-P501

Application In Synthesis of [ 622-29-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 622-29-7 ]

[ 622-29-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 6964-21-2 ]
  • [ 622-29-7 ]
  • (3SR,4RS)-1-methyl-4-phenyl-3-(thiophen-3-yl)azetidin-2-one [ No CAS ]
  • (3RS,4RS)-1-methyl-4-phenyl-3-(thiophen-3-yl)azetidin-2-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
58%; 19% With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; chloroform; at 70℃; for 20h; General procedure: The appropriate imine (0.762 mmol) and carboxylic acid (0.915 mmol, 1.2 eq.) were stirred in theappropriate solvent. NEt(i-Pr)2 (182 mg, 246 μL, 1.410 mmol, 1.85 eq.) and [T3P (364 mg, 1.14 mmol,1.5 eq. (728 mg of 50% wt. solution in THF)] were added by syringe and the reaction mixture stirred at70 C for 20 h. The reaction was poured into sat. NaHCO3 (10 mL) and extracted with CH2Cl2 (3 × 10mL). The combined organic phases were dried (MgSO4), filtered, and concentrated to give the crudematerial. At this stage the diastereoselectivity was determined using 1H NMR. The material was purifiedby column chromatography (see individual entries for eluting solvent systems).
  • 2
  • [ 622-29-7 ]
  • [ 475250-52-3 ]
  • 2-(4-methoxyphenyl)-N-methyl-1-phenylethan-1-amine [ No CAS ]
 

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