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Chemical Structure| 62640-03-3 Chemical Structure| 62640-03-3

Structure of 62640-03-3

Chemical Structure| 62640-03-3

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Product Details of [ 62640-03-3 ]

CAS No. :62640-03-3
Formula : C3H10ClNO
M.W : 111.57
SMILES Code : CNCCO.[H]Cl
MDL No. :N/A
InChI Key :LKAWQFHWVVSFTR-UHFFFAOYSA-N
Pubchem ID :12218838

Safety of [ 62640-03-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 62640-03-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 62640-03-3 ]

[ 62640-03-3 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 62640-03-3 ]
  • [ 4535-90-4 ]
YieldReaction ConditionsOperation in experiment
80% With sulfuryl dichloride In chloroform at 0℃; for 3 h; Reflux To a stirred solution of 2-(methylamino)ethanol hydrochloride (29.7 g, 1.0 eq) in 150 mL CHCI3 was added sulfuryl dichloride (41 g, 1.3 eq) dropwise at 0 °C. After refluxing for 3 h, the reaction was cooled to rt. Then solvent was removed in vacuo, the residue was suspended in 100 mL solution (CH2C12: petroleum ether = 1 : 10), and filtered to give the desired product (28 g, 80percent). :H NMR (400 MHz, DMSO-c ) δ 9.24 (brs, 2H), 3.93(t, J= 6.0 Hz, 2H), 3.28 (t, J= 6.0 Hz, 2H), 2.56 (s, 3H).
References: [1] Patent: WO2013/97773, 2013, A1, . Location in patent: Paragraph 0236; 0312.
[2] Patent: EP1893695, 2009, B1, . Location in patent: Page/Page column 31.
 

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