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Chemical Structure| 62681-98-5 Chemical Structure| 62681-98-5

Structure of 62681-98-5

Chemical Structure| 62681-98-5

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Product Details of [ 62681-98-5 ]

CAS No. :62681-98-5
Formula : C14H8F2N2O
M.W : 258.22
SMILES Code : FC1=CC=CC=C1C2=NN=C(C3=CC=CC=C3F)O2
MDL No. :MFCD00046071

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Application In Synthesis of [ 62681-98-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 62681-98-5 ]

[ 62681-98-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 18992-65-9 ]
  • [ 62681-98-5 ]
  • 2,5-bis(2-(2,7-dimethyl-9H-carbazol-9-yl)phenyl)-1,3,4-oxadiazole [ No CAS ]
YieldReaction ConditionsOperation in experiment
70% With potassium carbonate; In dimethyl sulfoxide; at 150℃; for 12.0h;Reflux; Inert atmosphere; General procedure: A mixture of 3,6-dimethyl-9H-carbazole (0.71 g, 3.6 mmol), 2,5-bis(2-fluorophenyl)-1,3,4-oxadiazole (0.43 g, 1.6 mmol) and K2CO3 (0.94 g, 6.8 mmol) in dimethyl sulfoxide (DMSO) (10 mL) was refluxed at 150oC for 12 h under an argon atmosphere. After cooling to room temperature, the mixture was poured into water, filtered and then the residue was purified by column chromatography on silica gel with hexane/CH2Cl2 (5:1 v/v) as eluent to give a white solid (0.85 g, 85% yield). 1H NMR (400 MHz, CDCl3), delta (TMS, ppm): 7.92 (s, 4H), 7.63 (t, J = 7.6 Hz, 2H), 7.51 (d, J = 7.2 Hz, 2H), 7.40 (t, J = 8.0 Hz, 2H), 7.24 (d, J = 8.0 Hz, 2H), 7.10 (d, J = 8.4 Hz, 4H), 6.76 (d, J = 8.4 Hz, 4H), 2.56 (s, 12H); 13C NMR (100 MHz, CDCl3), delta (TMS, ppm): 161.76, 139.89, 135.82, 132.56, 130.50, 128.84, 128.31, 127.07, 123.49, 122.78, 120.11, 108.93, 21.37; MALDI-TOF Mass (m/z): 607.505 (M+, calcd 608.258); Anal. Calcd for C42H32N4O: C 82.87, H 5.30, N 9.20; found: C 81.97, H 5.27, N 9.17.
References: [1]Tetrahedron,2020.
 

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