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Chemical Structure| 627531-51-5 Chemical Structure| 627531-51-5

Structure of 627531-51-5

Chemical Structure| 627531-51-5

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Product Details of [ 627531-51-5 ]

CAS No. :627531-51-5
Formula : C10H7N3
M.W : 169.18
SMILES Code : N#CC1=NC2=CC=C(N)C=C2C=C1
MDL No. :MFCD14584624

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Application In Synthesis of [ 627531-51-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 627531-51-5 ]

[ 627531-51-5 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 627531-51-5 ]
  • [ 5204-74-0 ]
  • [ 207121-46-8 ]
  • D-(-)-2-(6'-amino-2'-quinolyl)-Δ2-thiazoline-4-carboxylic acid, triethylamine salt [ No CAS ]
  • 2
  • [ 627531-51-5 ]
  • [ 207121-46-8 ]
  • [ 916660-37-2 ]
YieldReaction ConditionsOperation in experiment
6-amino-2-cyanoquinoline (100 mg, 0.59 mmol) was dissolved in 35 mL of methanol and the resultant solutionwas degassed with a gentle stream of nitrogen for 10 minutes Meanwhile, <strong>[207121-46-8]D-cysteine hydrochloride monohydrate</strong> (130mg, 0.74 mmol) was dissolved in 15 mL of water and the resultant solution was degassed with a gentle stream of nitrogenfor 5 minutes. The aqueous solution was then added to the organic solution and the resultant mixture was stirred undernitrogen for 4 hours. The volume of the solution was reduced under vacuum and it was then purified by semipreparativeHPLC with and acetonitrile (see general procedure: Mobile phase A: 100 mM NH4Ac, pH7).NMR (CD3CN): 8.25 ppm (d, 1H), 7.95 ppm (m, 2H), 7.46 ppm (dd, 1H), 7.06 ppm (s, 1H), 5.53 ppm (t, 1H), 3.96 ppm(m, 2H)ES+: 274.67 (M.W. 273.31)UV-Vis: 268 nm, 330 nm, and 373 nm.Extinction coefficient: 15, 320 (at 224 nm in MeOH), 13,020 (at 274 nm in MeOH)
 

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