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Chemical Structure| 6290-50-2 Chemical Structure| 6290-50-2

Structure of 6290-50-2

Chemical Structure| 6290-50-2

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Product Details of [ 6290-50-2 ]

CAS No. :6290-50-2
Formula : C6H10O3
M.W : 130.14
SMILES Code : CC(CC(COC)=O)=O
MDL No. :MFCD14702872
InChI Key :RZCMFVQMQKCVEN-UHFFFAOYSA-N
Pubchem ID :221734

Safety of [ 6290-50-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of [ 6290-50-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 6290-50-2 ]

[ 6290-50-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 6290-50-2 ]
  • [ 108290-86-4 ]
  • ethyl 2-(methoxymethyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxylate [ No CAS ]
  • ethyl 4-(methoxymethyl)-2-methylpyrrolo[1,2-a]pyrimidine-8-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
42%; 30% With acetic acid; at 110℃; for 0.5h; [00270] To a solution of ethyl 2-amino-lH-pyrrole-3-carboxylate (2.0 g, 13.0 mmol) in AcOH (20 mL) was added l-methoxypentane-2,4-dione (2.0 g, 15.6 mmol) and the solution was stirred at 110 C for 30 minutes then cooled and concentrated in vacuo. The residue was purified by silica gel column chromatography (EA:PE = 1 : 1) to give ethyl 2-(methoxymethyl)- 4-methylpyrrolo[l,2-a]pyrimidine-8-carboxylate (1.3 g, 42%) as a yellow solid and ethyl 4- (methoxymethyl)-2-methylpyrrolo[l,2-a]pyrimidine-8-carboxylate (970 mg, 30%) as a yellow oil. LC-MS m/z: 249.2 [M+H]+.
 

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