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Chemical Structure| 634-37-7 Chemical Structure| 634-37-7

Structure of 634-37-7

Chemical Structure| 634-37-7

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Product Details of [ 634-37-7 ]

CAS No. :634-37-7
Formula : C11H9NO2
M.W : 187.19
SMILES Code : CC1=NC2=C(C=CC=C2C(O)=O)C=C1
MDL No. :MFCD09754135

Safety of [ 634-37-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 634-37-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 634-37-7 ]

[ 634-37-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 18791-99-6 ]
  • [ 634-37-7 ]
  • 3-(4-bromothienyl-2-yl)-5-(2-methylquinolin-8-yl)-1,2,4-oxadiazole [ No CAS ]
YieldReaction ConditionsOperation in experiment
30% The 4-bromo-N-hydroxythiophene-2-carboximidamide (1 eq.) was coupled subsequently with 2-methylquinoline-8-carboxylic acid (1 eq.) in the presence of CDI (1.2 eq.) and Et3N (1 eq.) in DMF. The coupling was monitored by LC/MS. After the reaction was complete, acetic acid was charged and the mixture was fluxed overnight. After the reaction was complete, the desired compound, 3-(4-bromothienyl-2-yl)-5-(2-methylquinolin-8-yl)-1,2,4-oxadiazole B3 (100 mg), was purified via TLC and obtained in 30% yield.
 

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