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Chemical Structure| 642-29-5 Chemical Structure| 642-29-5

Structure of 642-29-5

Chemical Structure| 642-29-5

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Product Details of [ 642-29-5 ]

CAS No. :642-29-5
Formula : C17H12O
M.W : 232.28
SMILES Code : O=C(C1=C2C=CC=CC2=CC=C1)C3=CC=CC=C3
MDL No. :MFCD00046431

Safety of [ 642-29-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 642-29-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 642-29-5 ]

[ 642-29-5 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 642-29-5 ]
  • [ 902518-11-0 ]
  • C32H23NO [ No CAS ]
YieldReaction ConditionsOperation in experiment
40.8% To a 50 ml Schlenk tube was added 3-bromo-2-phenylquinoline (1 mmol, 284 mg) and anhydrous diethyl ether (5 ml). After the mixture was stirred at -78 ° C for 10 minutes, 1.6 M n-butyllithium (1 mL) was added dropwise and reacted at -78 ° C for 1 hour. The corresponding ketone fragment (186 mg, 0.8 mmol) was dissolved in anhydrous diethyl ether (10 mL), and then the mixture was applied to the mixture, and the mixture was applied to the above-mentioned reaction system by a syringe and stirred at -78 ° C for a few minutes and then transferred to room temperature and stirred overnight. Subsequently, the reaction was extracted with a saturated ammonium chloride solution and extracted with ethyl acetate (30 mL×3). The combined organic phase was washed with water, dried over anhydrous sodium sulfate, filtered, concentrated in vacuo, purified through the column to give a white solid (142mg, 40.8percent).
  • 2
  • [ 642-29-5 ]
  • [ 902518-11-0 ]
  • C32H21N [ No CAS ]
 

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