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Chemical Structure| 64670-84-4 Chemical Structure| 64670-84-4

Structure of 64670-84-4

Chemical Structure| 64670-84-4

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Product Details of [ 64670-84-4 ]

CAS No. :64670-84-4
Formula : C19H12N2O3
M.W : 316.31
SMILES Code : O=[N+](C1=CC=CC2=NC3=CC=CC=C3C(OC4=CC=CC=C4)=C21)[O-]

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Application In Synthesis of [ 64670-84-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 64670-84-4 ]

[ 64670-84-4 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 3321-03-7 ]
  • [ 64670-84-4 ]
  • (S)-2-[2-(1-Nitro-acridin-9-ylamino)-acetylamino]-3-phenyl-propionic acid [ No CAS ]
  • 2
  • [ 64670-84-4 ]
  • [ 2002-24-6 ]
  • [ 77280-93-4 ]
  • 1-nitro-9-hydroxyethylaminoacridine [ No CAS ]
YieldReaction ConditionsOperation in experiment
91% With hydrogenchloride; In phenol; 1-Nitro-9-Hydroxyethylaminoacridine This compound is synthesised generally using the methods described in EP 38579. Specifically, 2 g of <strong>[2002-24-6]2-amino-ethanol hydrochloride</strong> is added to 6.4 g of 1-nitro-9-phenoxyacridine dissolved in 20 g of freshly distilled phenol. The mixture is heated for 40 minutes at a temperature of 80 C. and then cooled, diluted with ether. It is then poured into dry ether that was acidified with an ethereal solution of hydrogen chloride. The orange colored precipitate of 1-nitro-9-(2-hydroxyethylamino)-acridine hydrochloride, obtained in this way is filtered and crystallized from dry ethanol. The melting point of the compounds obtained was 170 C., with decomposition. Yield 91%. Elementary analysis for the formula: C15H14N3O3Cl:calculated:56.47%; C, 4.42%; H, 13.17%; N. determined: 56.44%; C, 4.40%; H, 13.03%; N.
 

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