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Chemical Structure| 6484-25-9 Chemical Structure| 6484-25-9

Structure of 6484-25-9

Chemical Structure| 6484-25-9

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Product Details of [ 6484-25-9 ]

CAS No. :6484-25-9
Formula : C14H9ClN2
M.W : 240.69
SMILES Code : ClC1=C2C=CC=CC2=NC(C3=CC=CC=C3)=N1
MDL No. :MFCD00006713
InChI Key :OBHKONRNYCDRKM-UHFFFAOYSA-N
Pubchem ID :80977

Safety of [ 6484-25-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 6484-25-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 6484-25-9 ]

[ 6484-25-9 ] Synthesis Path-Downstream   1~8

  • 1
  • [ 6484-25-9 ]
  • [ 651-06-9 ]
  • N-(5-methoxypyrimidin-2-yl)-4-(2-phenylquinazolin-4-ylamino)benzenesulfonamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
84% In N,N-dimethyl-formamide; for 22h;Reflux; General procedure: A mixture of 4-chloro-2-phenylquinazoline (1, 2.42 g, 0.01 mol) and sulfonamides (0.012 mol) in dry dimethylformamide (10 mL) was refluxed for 22 h., then left to cool. The solid product formed upon pouring onto ice/water was collected by filtration and recrystallized from ethanol-dimethylformamide to give 2-18, respectively.
  • 2
  • [ 6484-25-9 ]
  • [ 526-08-9 ]
  • N-(1-phenyl-1H-pyrazol-5-yl)-4-(2-phenylquinazolin-4-ylamino)benzenesulfonamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
89% In N,N-dimethyl-formamide; for 22.0h;Reflux; General procedure: A mixture of 4-chloro-2-phenylquinazoline (1, 2.42 g, 0.01 mol) and sulfonamides (0.012 mol) in dry dimethylformamide (10 mL) was refluxed for 22 h., then left to cool. The solid product formed upon pouring onto ice/water was collected by filtration and recrystallized from ethanol-dimethylformamide to give 2-18, respectively.
  • 3
  • [ 6484-25-9 ]
  • [ 4949-69-3 ]
  • N-(4-iodo-3-methylphenyl)-2-phenylquinazolin-4-amine [ No CAS ]
  • 4
  • [ 6484-25-9 ]
  • [ 5369-19-7 ]
  • N-(3-(tert-butyl)phenyl)-2-phenylquinazolin-4-amine [ No CAS ]
  • 5
  • [ 90924-12-2 ]
  • [ 6484-25-9 ]
  • 2-phenyl-4-[(3-phenylisoxazol-5-yl)methoxy]quinazoline [ No CAS ]
YieldReaction ConditionsOperation in experiment
With triethylamine; In isopropyl alcohol; for 0.5h;Heating; The 0.24g (1mmol) of 2-phenyl-4-chloro-quinazoline is dissolved in 5 ml dry isopropanol, the solution is under stirring 0.175g (1mmol) 5-hydroxy methyl-3-phenyl-isoxazole 5 ml isopropanol solution is slowly dropped into the reaction system, then add 0.101g (1mmol) new jeung triethylamine, system stirring the mixture at room temperature for 30 min then, 60 C reaction, TLC detection after finishing the reaction, the reaction solution in vacuo, the residue is directly column separation (V (petroleum ether): V (ethyl acetate) = 5:1-2:1) to obtain the target compound 2-phenyl-4-[(3-phenylisoxazol-5-yl)methoxy]quinazoline (Q-11 in the following table). The rest of the compound in accordance with the 2-phenyl-4 - [(3-phenylisoxazol-5-yl)-methoxy]quinazoline. Its structure through IR, 1 HNMR, ESI-MS analyzing for the characterization. The preferred compound physical constant and the spectral data to a description of a form of list.
  • 6
  • [ 6484-25-9 ]
  • [ 1671-88-1 ]
  • N-(3,5-di(pyridine-2-yl)-4H-1,2,4-triazol-4-yl)-2-phenylquinqzolin-4-amine [ No CAS ]
  • 7
  • [ 1698-16-4 ]
  • [ 6484-25-9 ]
  • C30H18BrN3 [ No CAS ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; In N,N-dimethyl-formamide; at 140℃; for 5h; To the reaction flask, add 29.5g (100mmol) of 7-bromo-benzocarbazole and 16.5g of 4-chloro-2-phenylquinazoline(110mmol), 500mL of DMF and 43.3g (314mmol) of potassium carbonate, react at 140 C for 5h; stop the reaction after the reaction is completed, cool the reaction to room temperature, add water and filter, and the resulting solid is purified by recrystallization from toluene to obtain White powder M1
  • 8
  • [ 6484-25-9 ]
  • [ 1007-03-0 ]
  • 4-(cyclopropyl(phenyl)methoxy)-2-phenylquinazoline [ No CAS ]
 

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