Home Cart Sign in  
Chemical Structure| 64951-38-8 Chemical Structure| 64951-38-8

Structure of 64951-38-8

Chemical Structure| 64951-38-8

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 64951-38-8 ]

CAS No. :64951-38-8
Formula : C8H17ClN2O2
M.W : 208.69
SMILES Code : O=C(OCC)NC1CCNCC1.[H]Cl
MDL No. :MFCD13196158

Safety of [ 64951-38-8 ]

Application In Synthesis of [ 64951-38-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 64951-38-8 ]

[ 64951-38-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 64951-38-8 ]
  • [ 84946-20-3 ]
  • mizolastine [ No CAS ]
  • Ethyl[1-{1-[(4-fluorophenyl)-methyl]-1H-benzimidazol-2-yl}-4-piperidyl]carbamate [ No CAS ]
YieldReaction ConditionsOperation in experiment
With sodium hydroxide; sodium methylate; In methanol; 1.1.1. 19 g (0.09 mole) of ethyl 4-piperidylcarbamate hydrochloride is solubilized in 120 ml of methanol and neutralized with 17.2 ml of 5.3N sodium methylate. The mixture is filtered and the filtrate evaporated to dryness. The evaporation residue is then mixed with 21.6 g (0.083 mole) of 2-chloro-1-[(4-fluorophenyl)methyl]-1H-benzimidazole and heated to 140 C. for 5 hours. The reaction mass is taken up with methylene chloride and alkalinized with 2N sodium hydroxide. The organic phase is washed with water, dried, filtered and evaporated. The oil obtained is chromatographed on silica (eluent: methylene chloride/methanol, 97.5:2.5). Ethyl[1-{1-[(4-fluorophenyl)-methyl]-1H-benzimidazol-2-yl}-4-piperidyl]carbamate is obtained. M.p. 136 C.
 

Historical Records

Technical Information

Categories