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Chemical Structure| 65832-21-5 Chemical Structure| 65832-21-5

Structure of 65832-21-5

Chemical Structure| 65832-21-5

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Product Details of [ 65832-21-5 ]

CAS No. :65832-21-5
Formula : C8H9F3O5S
M.W : 274.21
SMILES Code : O=C(OC)C1=C(CCC1)OS(=O)(C(F)(F)F)=O
MDL No. :MFCD22570652
InChI Key :YXSARWFSYZHULU-UHFFFAOYSA-N
Pubchem ID :10880291

Safety of [ 65832-21-5 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H312-H332-H335-H314
Precautionary Statements:P260-P264-P270-P271-P280-P301+P330+P331-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P403+P233-P405-P501
Class:8
UN#:1760
Packing Group:

Application In Synthesis of [ 65832-21-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 65832-21-5 ]

[ 65832-21-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 65832-21-5 ]
  • [ 612845-44-0 ]
  • methyl 2-(6-ethoxypyridin-3-yl)cyclopent-1-ene-1-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; In 1,4-dioxane; water; at 80℃; for 2h;Inert atmosphere; A suspension of methyl 2-(((trifluoromethyl)sulfonyl)oxy)cyclopent-1- enecarboxylate (200 mg, 0.73 mmol), (Ph3P)2PdCl2 (51 mg, 0.073 mmol), 6- ethoxypyridine-3-boronic acid (244 mg, 1.46 mmol) and sodium carbonate (1.09 ml_ of a 2 M aq. solution, 2.18 mmol) in 1 ,4-dioxane (7 ml_) under nitrogen was heated to 80 C for 2 hrs. The suspension was cooled to room temperature, filtered through CELITE, washed with ethyl acetate, dried over MgSCU and concentrated under reduced pressure to yield a residue. The residue was purified by chromatography (12 g), eluting with 2 to 12% (1030) EA/heptane to yield methyl 2-(6-ethoxypyridin-3-yl)cyclopent-1-ene-1- carboxylate. Calculated for C14H17NO3: 248.1 (M+1); Measured: 248.3.
 

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