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Chemical Structure| 658695-85-3 Chemical Structure| 658695-85-3

Structure of 658695-85-3

Chemical Structure| 658695-85-3

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Product Details of [ 658695-85-3 ]

CAS No. :658695-85-3
Formula : C11H8N4O2
M.W : 228.21
SMILES Code : O=C(C1=CNC(C2=NNC3=NC=CC=C32)=C1)O
MDL No. :MFCD20528381

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Application In Synthesis of [ 658695-85-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 658695-85-3 ]

[ 658695-85-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 658695-85-3 ]
  • [ 15205-15-9 ]
  • [ 76-05-1 ]
  • (x)C2HF3O2*C18H13ClFN5O [ No CAS ]
YieldReaction ConditionsOperation in experiment
29.6% (0.14 mmol, 31.9 mg) was dissolved in 1 mL of dimethyl sulfoxide (DMSO), to which were added HOBt (0.35 mmol, 49.43 mg), EDCI · HCl (0.35 mmol, 68.42 mg), DIEA (0.56 mmol, 73.79 mg). After stirring at room temperature for 15 minutes, (0.14 mmol, 22.82 mg) was added. The reaction was carried out at room temperature for 5 hours. The reaction system was extracted with water/ethyl acetate (3 x 15 mL), then the organic phase was washed with saturated sodium chloride solution, dried with anhydrous sodium sulfate, concentrated, purified by reverse phase preparative HPLC (using 0.35% trifluoroacetic acid-containing aqueous solution and methanol as mobile phase), and vacuum concentrated to obtain compound III-f-1 (15.3 mg, 29.6%).
 

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