630-580-1088 sales@ambeed.com
Structure Search

List Search MOL Search Structure Search

0
Chemistry
Boronic acids/esters >>1,3,2-DioxaborinaneAliphatic BoronsAromatic BoronsBCATBoric AcidsMIDA BoronatesOther BoronatesOther BoronsOxaborolesCatalysis Chemistry >>Achiral Crown LigandsC-H ActivationCarbon-Donor LigandsChiral Carbon LigandsChiral Crown LigandsChiral Olefin LigandsCross-CouplingCross-Coupling Using Transition Metal CatalystsDACH or Trost LigandsChemical Biology >>Conjugation Chemistry
GlycoscienceLinkers and CrosslinkersNucleic Acid ChemistryPEGylationPeptide ChemistryPhotolabile Protecting GroupHeterocyclic Building Blocks >>AcridinesAliphatic HeterocyclesAromatic HeterocyclesAzetidinesBenzimidazolesBenzisoxazolesBenzodioxansBenzofuransBenzothiazolesInorganic reagents >>Inorganic ReagentOrganic Building Blocks >>Acid AnhydridesAcyl ChloridesAlcohols
AldehydesAliphatic Chain HydrocarbonsAliphatic Cyclic HydrocarbonsAlkenesAlkylsAlkynesOrganometallic Reagents >>Grignard ReagentsOrganoarsenicOrganobismuthOrganoboronOrganogermaniumOrganolithiumOrganomercuryOrganosiliconOrganotinSpecialty Synthesis >>Enzyme-Mediated SynthesisFluorous SynthesisIonic LiquidsSolid Supported SynthesisStains and Dyes >>
Acid DyesAzoic DyesBasic DyesDirect DyesDisperse DyesDye IntermediatesMordant DyesOil DyesOther Stains and DyesSynthetic Reagents >>Acids and BasesC-C Bond FormationC-X Bond Formation (Halogen)C-X Bond Formation (Non-Halogen)Chelation and Complexation CompoundsCondensation AgentsCouplingDehydrating ReagentsFluorination Reagent
Pharmaceutical Intermediates
Analgesics >>BenzhydrocodoneBicifadineCapsaicinCelecoxibDebio-0827DexamethasoneElagolix SodiumEsketamine HydrochlorideIbuprofen SodiumAnesthetics >>CiprofolEsketamine HydrochlorideFospropofol Fospropofol DisodiumLevobupivacaine RemimazolamRemimazolam BesilateRemimazolam BesylateRopivacaineAnti-Addiction Agents >>Kakonein
Lofexidine HydrochlorideVarenicline Anti-inflammatory Agents >>ApremilastAsunaprevirATB-346 RelatedBalsalazide BaricitinibBencycloquidium BromideBudesonideCefiderocol Sulfate TosylateCeftaroline Fosamil AcetateAntibacterials >>AFN-1252 RelatedAlatrofloxacin Bedaquiline FumarateBesifloxacin BrilacidinCaspofungin AcetateCefiderocol Sulfate TosylateCefilavancinCeftaroline Fosamil
Anticonvulsants >>BrivaracetamCannabidiolEscitalopram OxalateEslicarbazepine Acetate RelatedFosphenytoinGabapentin EnacarbilJNJ-10234094LacosamideLevetiracetam RelatedAntidementia Agents >>Azeliragon RelatedDavunetideDonepezil HydrochlorideDonepezil RelatedEnsaculinFlorbetaben Flortaucipir F 18Flutemetamol IdalopirdineAntidepressants >>4-Chlorokynurenine
AgomelatineAgomelatine RelatedAllopregnanolone RelatedAmibegronAmitifadineAripiprazole RelatedBasimglurantBefloxatoneAntiemetics >>AprepitantAprepitant RelatedDolasetron RelatedDolasetron Mesylate HydrateFosaprepitant DimeglumineFosaprepitant RelatedOlanzapinePalonosetron RelatedPalonosetron HydrochlorideAntifungals >>Anidulafungin RelatedCabotegravirMore >>
Inhibitors/Agonists
ADC >>ADC AntibodyADC LinkerADC Linker with PayloadADC ToxinAntibody-Drug Conjugates (ADCs)Drug-Linker Conjugates for ADCAngiogenesis >>ALKBcr-AblBTKEGFRFAKFGFRFLT3HER2HIFAnti-infection >>3CLproAntibacterialAntibioticAntifungal
AntiparasiticAntiprotozoalAntiviralArenavirusBVDVApoptosis >>Apoptosis InducerBcl-2Bcl-6BRKc-Mycc-RETC/EBPCARDCaspaseAutophagy >>Atg4ATG4BATTECsAUTACsAutophagyBeclin1
FKBPLC3LRRK2Biochemical Reagent >>Cell Cycle >>AntifolateAPCAurora KinaseBUBCasein KinaseCdc25CDKChkCRISPR/Cas9Cytoskeleton >>ActinArp2/3 ComplexCYTHCytoplasmic DyneinDynaminFAKMore >>
Material Science
Aggregation-Induced Emission >>Other AIE BlocksTetraphenylethylene SeriesCOFs Linkers >>Aldehyde COFs LinkersAlkynyl COFs LinkersAmine COFs LinkersBoric COFs LinkersCyano COFs LinkersMultifunctional COFs linkersOther COFs linkersTriptycene SeriesElectronic Materials >>Battery MaterialsDye-Sensitized Solar Cell (DSSC) MaterialsElectronic MaterialLiquid Crystal (LC) MaterialsMolecular ConductorsOrganic Light-Emitting Diode (OLED) MaterialsOrganic Solar Cell (OPV) MaterialsOrganic Transistor (OFET) MaterialsPerovskite Solar Cell (PSC) MaterialsMagnetic Materials >>Magnetic Ionic LiquidsMagnetic MaterialMagnetic Metal Complexes
Organic Radicals Material Chemical Compounds >>Ligands for Functional Metal ComplexesLiquid Crystal (LC) Building BlocksPhthalocyanine Building BlocksPolymer and Macromolecule Semiconductor Building BlocksSmall Molecule Semiconductor Building BlocksSolubility Enhancing Reagents Supramolecular Host Materials MOF Ligands >>Carboxylic Acid MOF LigandsCarboxylic Acid Nitrogen-Containing Mixed MOF LigandsNitrogen-Containing MOF LigandsOther MOF LigandsNanomaterials >>Carbon NanomaterialsCeramic MembranesDendrimersGold NanoparticlesIron Oxide NanoparticlesMaterials by ApplicationMesoporous MaterialsMetals and Metal AlloysNano Minerals: NanoclaysOLED Materials >>Dopant
HostHTMOLED IntermediatesOther OLED related materialsOptical Materials >>Coumarin DyesCyanine and Squarylium DyesDCM DyesDipyrromethene DyesFluorescence MaterialsFluorescent ProbesHeat and Pressure Sensitive DyesNear-Infrared (NIR) DyesOrganic Non-Linear Optical (NLO) MaterialsOrganic Pigments >>Organic PigmentOther Materials >>Material OtherPolymer Science >>MonomersPolymer AdditivesPolymerization ReagentsPolymersResins
Contact Us
Home Cart 0 Sign in  
Chemistry
Organic Building Blocks
Pyridines
pyridine-2-sulfonamide
5-Methyl-2-pyridinesulfonamide
Chemistry
Organic Building Blocks
Heterocyclic Building Blocks
Pyridines
Amines Sulfamides
pyridine-2-sulfonamide

[ CAS No. 65938-77-4 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 65938-77-4
Chemical Structure| 65938-77-4
Structure of 65938-77-4 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

For Research Only 120K+ Compounds Competitive Price 1-2 Day Shipping

Quality Control of [ 65938-77-4 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 65938-77-4 ]

SDS Specification
Alternatived Products of [ 65938-77-4 ]
Product Citations

Product Details of [ 65938-77-4 ]

CAS No. :65938-77-4 MDL No. :MFCD00661363
Formula : C6H8N2O2S Boiling Point : No data available
Linear Structure Formula :- InChI Key :HXURYNQXMBRJLU-UHFFFAOYSA-N
M.W : 172.20 Pubchem ID :3614199
Synonyms :

Calculated chemistry of [ 65938-77-4 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 11
Num. arom. heavy atoms : 6
Fraction Csp3 : 0.17
Num. rotatable bonds : 1
Num. H-bond acceptors : 4.0
Num. H-bond donors : 1.0
Molar Refractivity : 40.2
TPSA : 81.43 Ų

Pharmacokinetics

GI absorption : High
BBB permeant : No
P-gp substrate : No
CYP1A2 inhibitor : No
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : No
Log Kp (skin permeation) : -7.27 cm/s

Lipophilicity

Log Po/w (iLOGP) : 0.89
Log Po/w (XLOGP3) : 0.11
Log Po/w (WLOGP) : 1.12
Log Po/w (MLOGP) : -0.96
Log Po/w (SILICOS-IT) : -0.06
Consensus Log Po/w : 0.22

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 1.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -1.31
Solubility : 8.35 mg/ml ; 0.0485 mol/l
Class : Very soluble
Log S (Ali) : -1.38
Solubility : 7.26 mg/ml ; 0.0421 mol/l
Class : Very soluble
Log S (SILICOS-IT) : -1.97
Solubility : 1.83 mg/ml ; 0.0106 mol/l
Class : Soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 0.0 alert
Leadlikeness : 1.0
Synthetic accessibility : 1.91

Safety of [ 65938-77-4 ]

Signal Word:Warning Class:
Precautionary Statements:P261-P305+P351+P338 UN#:
Hazard Statements:H315-H319-H335 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 65938-77-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 65938-77-4 ]

[ 65938-77-4 ] Synthesis Path-Downstream   1~14

  • 1
  • [ 292638-84-7 ]
  • [ 65938-77-4 ]
  • [ 796034-71-4 ]
Reference： [1]Journal of Organic Chemistry,2008,vol. 73,p. 2862 - 2870
[2]Organic Letters,2004,vol. 6,p. 4109 - 4112
[3]Journal of Organic Chemistry,2006,vol. 71,p. 5876 - 5880
[4]Journal of Organic Chemistry,2008,vol. 73,p. 2862 - 2870
  • 2
  • [ 498-66-8 ]
  • [ 65938-77-4 ]
  • (1S,2R,4S,5R)-3-(5-Methyl-pyridine-2-sulfonyl)-3-aza-tricyclo[3.2.1.02,4]octane [ No CAS ]
Reference： [1]Organic Letters,2004,vol. 6,p. 4109 - 4112
  • 3
  • [ 622-97-9 ]
  • [ 65938-77-4 ]
  • N-(5-methyl-2-pyridinesulfonyl)(4-methylphenyl)aziridine [ No CAS ]
Reference： [1]Organic Letters,2004,vol. 6,p. 4109 - 4112
  • 4
  • [ 931-88-4 ]
  • [ 65938-77-4 ]
  • 9-(5-methyl-pyridine-2-sulfonyl)-9-aza-bicyclo[6.1.0]nonane [ No CAS ]
Reference： [1]Organic Letters,2004,vol. 6,p. 4109 - 4112
  • 5
  • [ 100-13-0 ]
  • [ 65938-77-4 ]
  • N-(5-methyl-2-pyridinesulfonyl)(4-nitrophenyl)aziridine [ No CAS ]
Reference： [1]Organic Letters,2004,vol. 6,p. 4109 - 4112
  • 6
  • [ 873-66-5 ]
  • [ 65938-77-4 ]
  • trans-N-(5-methyl-2-pyridinesulfonyl)-2-methyl-3-phenylaziridine [ No CAS ]
Reference： [1]Organic Letters,2004,vol. 6,p. 4109 - 4112
  • 7
  • [ 33143-29-2 ]
  • [ 65938-77-4 ]
  • 2,2-dimethyl-1-(5-methyl-pyridine-2-sulfonyl)-1,1a,2,7b-tetrahydro-3-oxa-1-aza-cyclopropa[<i>a</i>]naphthalene-6-carbonitrile [ No CAS ]
Reference： [1]Organic Letters,2004,vol. 6,p. 4109 - 4112
  • 8
  • [ 2039-82-9 ]
  • [ 65938-77-4 ]
  • N-(5-methyl-2-pyridinesulfonyl)(4-bromophenyl)aziridine [ No CAS ]
Reference： [1]Organic Letters,2004,vol. 6,p. 4109 - 4112
  • 9
  • [ 2628-16-2 ]
  • [ 65938-77-4 ]
  • N-(5-methyl-2-pyridinesulfonyl)(4-acetyloxyphenyl)aziridine [ No CAS ]
Reference： [1]Organic Letters,2004,vol. 6,p. 4109 - 4112
  • 10
  • [ 3240-34-4 ]
  • [ 65938-77-4 ]
  • [ 84494-81-5 ]
  • N-[2-(4-tert-butyldimethylsilyloxyphenyl)-2-(acetyloxy)ethyl](5-methyl-2-pyridine)sulfonamide [ No CAS ]
Reference： [1]Organic Letters,2004,vol. 6,p. 4109 - 4112
  • 11
  • [ 766-90-5 ]
  • [ 65938-77-4 ]
  • trans-N-(5-methyl-2-pyridinesulfonyl)-2-methyl-3-phenylaziridine [ No CAS ]
  • cis-N-(5-methyl-2-pyridinesulfonyl)-2-methyl-3-phenylaziridine [ No CAS ]
Reference： [1]Organic Letters,2004,vol. 6,p. 4109 - 4112
  • 12
  • [ 394-46-7 ]
  • [ 65938-77-4 ]
  • N-(5-methyl-2-pyridinesulfonyl)(2-fluorophenyl)aziridine [ No CAS ]
Reference： [1]Organic Letters,2004,vol. 6,p. 4109 - 4112
  • 13
  • [ 827-54-3 ]
  • [ 65938-77-4 ]
  • 5-methyl-2-[[2-(naphthalen-2-yl)aziridin-1-yl]sulfonyl]pyridine [ No CAS ]
Reference： [1]Organic Letters,2004,vol. 6,p. 4109 - 4112
  • 14
  • [ 2039-86-3 ]
  • [ 65938-77-4 ]
  • N-(5-methyl-2-pyridinesulfonyl)(3-bromophenyl)aziridine [ No CAS ]
Reference： [1]Organic Letters,2004,vol. 6,p. 4109 - 4112

Tags: 65938-77-4 synthesis path| 65938-77-4 SDS| 65938-77-4 COA| 65938-77-4 purity| 65938-77-4 application| 65938-77-4 NMR| 65938-77-4 COA| 65938-77-4 structure

Recommend Products
Same Skeleton Products
Related Products
Isomers
Categories
Chemistry
Heterocyclic Building Blocks
Pyridines
pyridine-2-sulfonamide
Chemistry
Organic Building Blocks
Sulfamides
pyridine-2-sulfonamide
Chemistry
Organic Building Blocks
Amines

Technical Information

• Buchwald-Hartwig C-N Bond and C-O Bond Formation Reactions • Chan-Lam Coupling Reaction • Hydride Reductions • Leuckart-Wallach Reaction • Mannich Reaction • Petasis Reaction • Preparation of Amines • Reactions of Amines • Specialized Acylation Reagents-Vilsmeier Reagent • Ugi Reaction
Historical Records

Related Functional Groups of
[ 65938-77-4 ]

Amines

Chemical Structure| 63636-89-5

[ 63636-89-5 ]

Pyridine-2-sulfonamide

Similarity: 0.92

Chemical Structure| 65938-79-6

[ 65938-79-6 ]

3-Methylpyridine-2-sulfonamide

Similarity: 0.87

Chemical Structure| 75903-58-1

[ 75903-58-1 ]

6-Aminopyridine-2-sulfonamide

Similarity: 0.84

Chemical Structure| 856013-04-2

[ 856013-04-2 ]

6-Bromopyridine-2-sulfonamide

Similarity: 0.77

Chemical Structure| 314250-03-8

[ 314250-03-8 ]

N,N-Diethylpyridine-2-sulfonamide

Similarity: 0.73

Sulfamides

Chemical Structure| 63636-89-5

[ 63636-89-5 ]

Pyridine-2-sulfonamide

Similarity: 0.92

Chemical Structure| 65938-79-6

[ 65938-79-6 ]

3-Methylpyridine-2-sulfonamide

Similarity: 0.87

Chemical Structure| 75903-58-1

[ 75903-58-1 ]

6-Aminopyridine-2-sulfonamide

Similarity: 0.84

Chemical Structure| 856013-04-2

[ 856013-04-2 ]

6-Bromopyridine-2-sulfonamide

Similarity: 0.77

Chemical Structure| 314250-03-8

[ 314250-03-8 ]

N,N-Diethylpyridine-2-sulfonamide

Similarity: 0.73

Related Parent Nucleus of
[ 65938-77-4 ]

Pyridines

Chemical Structure| 63636-89-5

[ 63636-89-5 ]

Pyridine-2-sulfonamide

Similarity: 0.92

Chemical Structure| 65938-79-6

[ 65938-79-6 ]

3-Methylpyridine-2-sulfonamide

Similarity: 0.87

Chemical Structure| 75903-58-1

[ 75903-58-1 ]

6-Aminopyridine-2-sulfonamide

Similarity: 0.84

Chemical Structure| 856013-04-2

[ 856013-04-2 ]

6-Bromopyridine-2-sulfonamide

Similarity: 0.77

Chemical Structure| 314250-03-8

[ 314250-03-8 ]

N,N-Diethylpyridine-2-sulfonamide

Similarity: 0.73

; ;