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Chemical Structure| 66548-54-7 Chemical Structure| 66548-54-7

Structure of 66548-54-7

Chemical Structure| 66548-54-7

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Product Details of [ 66548-54-7 ]

CAS No. :66548-54-7
Formula : C11H6ClN3
M.W : 215.64
SMILES Code : N#CC1=CC=C(C2=NN=C(Cl)C=C2)C=C1

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Application In Synthesis of [ 66548-54-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 66548-54-7 ]

[ 66548-54-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 35418-07-6 ]
  • [ 66548-54-7 ]
  • 6-(4-Cyanophenyl)-3-[4-[2-(methoxycarbonyl)-ethyl]-phenylamino]-pyridazine [ No CAS ]
YieldReaction ConditionsOperation in experiment
In dichloromethane; EXAMPLE XIX 6-(4-Cyanophenyl)-3-[4-[2-(methoxycarbonyl)-ethyl]-phenylamino]-pyridazine 0.60 g of 3-chloro-6-(4-cyanophenyl)-pyridazine are heated to 140-150 C. for 1.5 hours with 1.70 g of <strong>[35418-07-6]4-[2-(methoxycarbonyl)-ethyl]-aniline</strong>. The cooled melt is dissolved in methylene chloride and the organic phase is extracted with 1N sodium hydroxide solution. Drying the organic phase over sodium sulphate and evaporating off the solvent yields a solid which is chromatographed over silica gel. Yield: 1.80 g (95% of theory), Melting point: 212-217 C., Rf value: 0.34 (silica gel; methylene chloride/methanol=20:1)
 

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