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Chemical Structure| 668-94-0 Chemical Structure| 668-94-0

Structure of 668-94-0

Chemical Structure| 668-94-0

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Product Details of [ 668-94-0 ]

CAS No. :668-94-0
Formula : C15H12N2
M.W : 220.27
SMILES Code : C1(C2=CC=CC=C2)=C(C3=CC=CC=C3)NC=N1
MDL No. :MFCD00005198
InChI Key :CPHGOBGXZQKCKI-UHFFFAOYSA-N
Pubchem ID :69588

Safety of [ 668-94-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 668-94-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 668-94-0 ]

[ 668-94-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 668-94-0 ]
  • [ 57616-74-7 ]
  • [ 473826-15-2 ]
YieldReaction ConditionsOperation in experiment
68% With potassium carbonate; In acetonitrile; for 24h;Heating / reflux; EXAMPLE 1 Synthesis of 4-[3-(4,5-diphenylimidazol-1-yl)-propyl]morpholine of the Following Formula [0236] [CHEMMOL-00002] [0237] 200 ml of acetonitrile, 8 g of 4,5-diphenylimidazole (36 mmol) sold by the company Acros, 10 g of K2CO3 (72 mmol) and then 11 g of morpholinepropyl chloride in hydrochloride form (1.5 equivalents) are placed in a three-necked flask. The mixture is refluxed for 24 hours. After cooling, the mixture is evaporated to dryness under vacuum. The mixture is dissolved in 100 ml of water and then extracted with ethyl acetate. The organic phase is washed with water and then dried over sodium sulphate. After evaporation to dryness, the oil obtained is precipitated by adding diethyl ether. The precipitate is filtered off and then recrystallized from a water/ethyl alcohol mixture (20/80). [0238] 8.6 g of product are obtained in a yield of 68%. Analysis [0239] 1H NMR (400 MHz, in DMSO-d6): delta (ppm)=1.6 (m, 2H); 2.1 (m, 6H); 3.4 (m, 4H); 3.8 (t, 2H); 7.1-7.5 (4m, 10H); 7.8 (s, 1H)
 

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