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Chemical Structure| 6833-13-2 Chemical Structure| 6833-13-2

Structure of 6833-13-2

Chemical Structure| 6833-13-2

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Product Details of [ 6833-13-2 ]

CAS No. :6833-13-2
Formula : C13H10ClNO
M.W : 231.68
SMILES Code : O=C(NC1=CC=CC=C1)C2=CC=CC=C2Cl
MDL No. :MFCD00016336

Safety of [ 6833-13-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 6833-13-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 6833-13-2 ]

[ 6833-13-2 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 6833-13-2 ]
  • [ 60940-34-3 ]
YieldReaction ConditionsOperation in experiment
54% With selenium; copper(l) iodide; 1,10-Phenanthroline; potassium carbonate; In N,N-dimethyl-formamide; at 110℃; for 24h;Inert atmosphere; General procedure: Copper iodide (82 mg, 0.4 mmol) and 1,10-phenanthroline (78 mg, 0.4 mmol) were added into DMF (3 mL) in a single neck flask. Resulted brownish solution was stirred for 15 min and then 2-chloro-N-phenylbenzamide22 (0.20 g, 0.86 mmol), selenium powder (81 mg, 1.0 mmol), and potassium carbonate powder (178 mg, 1.3 mmol) were added sequentially to same reaction flask. Brown colored reaction mixture was refluxed at 110 C using refluxing condenser under nitrogen atmosphere. Progress of reaction was monitored by TLC. Reaction mixture was refluxed for 24 h. After this, reaction mixture was poured into brine solution (50 mL) and stirred for 3 h. Product was precipitated as white solid, which was collected by filtration over Buchner funnel, washed with water (15 mL×3), dried in air, dissolved in ethyl acetate, and concentrated over rotary evaporator. The resulted brown solid was purified by column chromatography using hexane/ethyl acetate (8:2) over silica gel. Yield 128 mg (54%). Characterization data (mp, 1H NMR, Mass, and IR) is in accordance with reported one.19
  • 2
  • [ 7782-49-2 ]
  • [ 6833-13-2 ]
  • [ 60940-34-3 ]
 

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